EGF, His, Canine

EGF, His, Canine

The epidermal growth factor (EGF) family of peptides encodes several proteins that can function as growth factors. The EGF-like peptides, with the exception of proteins of the EGF-CFC subfamily, bind and activate tyrosine kinase receptors that belong to the erbB family.
Z04696
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Product Introduction
Species Canine
Protein Construction
His EGF (Asn973-Arg1024)
Accession # Q9BEA0
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized EGF, His, Canine at 1μg/ml (100μl/well) on the plate can bind Human EGFR, hFc Tag. Test result was comparable to standard batch.
Expression System E.coli
Theoretical Molecular Weight 13.61 kDa
Apparent Molecular Weight The protein migrates to 16-22 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Background
Target Background The epidermal growth factor (EGF) family of peptides encodes several proteins that can function as growth factors. The EGF-like peptides, with the exception of proteins of the EGF-CFC subfamily, bind and activate tyrosine kinase receptors that belong to the erbB family.
Synonyms HOMG4; URG

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.