PLAU/uPA[Biotin], His & Avi, Mouse
PLAU/uPA[Biotin], His & Avi, Mouse

The purity of PLAU/uPA[Biotin], His & Avi, Mouse is greater than 95% as determined by SEC-HPLC.

PLAU/uPA[Biotin], His & Avi, Mouse

PLAU/uPA[Biotin], His & Avi, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

PLAU/uPA[Biotin], His & Avi, Mouse

Mouse uPAR isoform 1, His Tag immobilized on CM5 Chip can bind PLAU/uPA[Biotin], His & Avi, Mouse, His Tag with an affinity constant of 0.33 μM as determined in SPR assay (Biacore T200).

PLAU/uPA[Biotin], His & Avi, Mouse

Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
Z04677
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Product Introduction
Species Mouse
Protein Construction
PLAU/Upa (Gly21-Phe433)
Accession # P06869		 His Avi
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 49.00 kDa
Apparent Molecular Weight Due to enzyme lysis and glycosylation, the protein migrates to 30-35 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Dissolve the lyophilized protein in 20mM PB, 150mM NaCl (pH 6.0). It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • PLAU/uPA[Biotin], His & Avi, Mouse
    • PLAU/uPA[Biotin], His & Avi, Mouse

    The purity of PLAU/uPA[Biotin], His & Avi, Mouse is greater than 95% as determined by SEC-HPLC.

  • PLAU/uPA[Biotin], His & Avi, Mouse
    • PLAU/uPA[Biotin], His & Avi, Mouse

    PLAU/uPA[Biotin], His & Avi, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • PLAU/uPA[Biotin], His & Avi, Mouse
    • PLAU/uPA[Biotin], His & Avi, Mouse

    Mouse uPAR isoform 1, His Tag immobilized on CM5 Chip can bind PLAU/uPA[Biotin], His & Avi, Mouse, His Tag with an affinity constant of 0.33 μM as determined in SPR assay (Biacore T200).


Background
Target Background Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
Synonyms PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.