Immobilized Human Trail, No Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for TRAIL R1/DR4/TNFRSF10A[Biotin], His & Avi, Human, His Tag with the EC50 of 0.38 μg/ml determined by ELISA.
The purity of TRAIL R1/DR4/TNFRSF10A[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.
TRAIL R1/DR4/TNFRSF10A[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
TRAIL R1/DR4/TNFRSF10A[Biotin], His & Avi, Human, His-Avi Tag immobilized on CM5 Chip can bind Human TRAIL, No Tag with an affinity constant of 0.315 nM as determined in SPR assay (Biacore T200).
TRAIL R1/DR4/TNFRSF10A[Biotin], His & Avi, Human
Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily.The expression of apoptosis-inducing TRAIL-R1 and TRAIL-R2 and of the decoy receptors TRAIL-R3 and TRAIL-R4 was systematically studied in all developmental stages of peripheral B cells isolated from the blood and secondary lymphoid organs. Expression of TRAIL-Rs is modulated along development, with highest levels observed in germinal center B cells.
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