TFPI[Biotin], His & Avi, Human
TFPI[Biotin], His & Avi, Human

TFPI[Biotin], His & Avi, Human

TFPI[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

TFPI[Biotin], His & Avi, Human

Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and has recently been associated with breast cancer cell development.
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Product Introduction
Species Human
Protein Construction
TFPI (Asp29-Lys282)
Accession # P10646-1		 His Avi
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, the IC50 value is < 0.75 nM. Test result meets the standard.
Expression System HEK293
Theoretical Molecular Weight 32.1 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • TFPI[Biotin], His & Avi, Human
    • TFPI[Biotin], His & Avi, Human

  • TFPI[Biotin], His & Avi, Human
    • TFPI[Biotin], His & Avi, Human

    TFPI[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and has recently been associated with breast cancer cell development.
Synonyms LACI; TFPI1; EPI; TFI; convertin; TFPI

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.