SIRP Beta/CD172b[Biotin], His & Avi, Human
SIRP Beta/CD172b[Biotin], His & Avi, Human

The purity of SIRP Beta/CD172b[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.

SIRP Beta/CD172b[Biotin], His & Avi, Human

SIRP Beta/CD172b[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SIRP Beta/CD172b[Biotin], His & Avi, Human

SIRP beta 1 is a type I transmembrane protein belonging to the SIRP family within the Ig superfamily. Members of this family are characterized by an extracellular region containing a V-set Ig domain containing a J-like sequence and two C1-set Ig domains.SIRP beta 1 is immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
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Product Introduction
Species Human
Protein Construction
SIRP Beta/CD172b (Glu30-Ala369)
Accession # O00241-1		 His Avi
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 40 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • SIRP Beta/CD172b[Biotin], His & Avi, Human
    • SIRP Beta/CD172b[Biotin], His & Avi, Human

    The purity of SIRP Beta/CD172b[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.

  • SIRP Beta/CD172b[Biotin], His & Avi, Human
    • SIRP Beta/CD172b[Biotin], His & Avi, Human

    SIRP Beta/CD172b[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background SIRP beta 1 is a type I transmembrane protein belonging to the SIRP family within the Ig superfamily. Members of this family are characterized by an extracellular region containing a V-set Ig domain containing a J-like sequence and two C1-set Ig domains.SIRP beta 1 is immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
Synonyms SIRP-beta-1 isoform 3; SIRPB1; CD172b; DKFZp686A05192; FLJ26614; 9930027N05Rik; SIRP-beta; Sirpb; Sirpb1; Sirpb1a;SIRP-β-1 isoform 3; SIRP-β

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.