IL-5 R alpha/CD125[Biotin], His & Avi, Human
IL-5 R Alpha/CD125[Biotin], His & Avi, Human

Immobilized Human IL-5, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for IL-5 R alpha/CD125[Biotin], His & Avi, Human, His Tag with the EC50 of 0.15 μg/ml determined by ELISA.

IL-5 R Alpha/CD125[Biotin], His & Avi, Human

The purity of IL-5 R alpha/CD125[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.

IL-5 R Alpha/CD125[Biotin], His & Avi, Human

IL-5 R alpha/CD125[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

IL-5 R alpha/CD125[Biotin], His & Avi, Human

Interleukin‑5 Receptor alpha (IL‑5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5.
Z04516
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Product Introduction
Species Human
Protein Construction
IL-5 R alpha/CD125 (Asp21-Glu335)
Accession # Q01344-1		 His Avi
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per ug by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized Human IL­5, His Tag at 2μg/ml (100μl/well) on the plate can bind IL-5 R alpha/CD125[Biotin], His & Avi, Human. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 38.7 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 55-60 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • IL-5 R Alpha/CD125[Biotin], His & Avi, Human
    • IL-5 R Alpha/CD125[Biotin], His & Avi, Human

    Immobilized Human IL-5, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for IL-5 R alpha/CD125[Biotin], His & Avi, Human, His Tag with the EC50 of 0.15 μg/ml determined by ELISA.

  • IL-5 R Alpha/CD125[Biotin], His & Avi, Human
    • IL-5 R Alpha/CD125[Biotin], His & Avi, Human

    The purity of IL-5 R alpha/CD125[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.

  • IL-5 R Alpha/CD125[Biotin], His & Avi, Human
    • IL-5 R Alpha/CD125[Biotin], His & Avi, Human

    IL-5 R alpha/CD125[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Interleukin‑5 Receptor alpha (IL‑5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5.
Synonyms CD125; CDw125CD125; HSIL5R3; IL-5 R alpha; IL-5R subunit alpha; IL5R; IL5RA; IL-5Ra; MGC26560

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.