Immobilized FGFR2 beta (IIIb) Domain[Biotin], Avi, Human, Avi Tag at 0.5 μg/ml (100 μl/Well) on streptavidin(5 μg/ml) precoated plate. Dose response curve for Anti-FGFR2 (IIIb) Antibody, hFc Tag with the EC50 of 1.8ng/ml determined by ELISA.
The purity of FGFR2 beta (IIIb) Domain[Biotin], Avi, Human is greater than 90% as determined by SEC-HPLC.
FGFR2 beta (IIIb) Domain[Biotin], Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
FGFR2 beta (IIIb) Domain[Biotin], Avi, Human
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains, referred to as the alpha isoform, or only IgII and IgIII, referred to as the beta isoform.
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