Fc gamma RI/CD64[Biotin], His & Avi, Human
Fc Gamma RI/CD64[Biotin], His & Avi, Human

The purity of Fc gamma RI/CD64[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.

Fc Gamma RI/CD64[Biotin], His & Avi, Human

Fc gamma RI/CD64[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Fc Gamma RI/CD64[Biotin], His & Avi, Human

Fc gamma RI/CD64[Biotin], His & Avi, Human, His-Avi Tag captured on CM5 Chip via Anti-His Antibody can bind Trastuzumab with an affinity constant of 0.91 nM as determined in SPR assay (Biacore T200).

Fc gamma RI/CD64[Biotin], His & Avi, Human

The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma RI (also known as CD64), Fc gamma RII (CD32), and Fc gamma RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type.
Z04449
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Product Introduction
Species Human
Protein Construction
Fc gamma RI/CD64 (Gln16-Pro288)
Accession # P12314-1		 His Avi
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis­Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1 EU per μg by the LAL method.
Biological Activity Fc gamma RI/CD64[Biotin], His & Avi, Human captured on CM5 Chip via Anti­His Antibody can bind Trastuzumab in SPR assay (Biacore T200). Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 33.5 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 55-68 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • Fc Gamma RI/CD64[Biotin], His & Avi, Human
    • Fc Gamma RI/CD64[Biotin], His & Avi, Human

    The purity of Fc gamma RI/CD64[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.

  • Fc Gamma RI/CD64[Biotin], His & Avi, Human
    • Fc Gamma RI/CD64[Biotin], His & Avi, Human

    Fc gamma RI/CD64[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • Fc Gamma RI/CD64[Biotin], His & Avi, Human
    • Fc Gamma RI/CD64[Biotin], His & Avi, Human

    Fc gamma RI/CD64[Biotin], His & Avi, Human, His-Avi Tag captured on CM5 Chip via Anti-His Antibody can bind Trastuzumab with an affinity constant of 0.91 nM as determined in SPR assay (Biacore T200).


Background
Target Background The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma RI (also known as CD64), Fc gamma RII (CD32), and Fc gamma RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type.
Synonyms CD64; CD64a; Fc gamma RI; FCG1; Fc-gamma RIA; FCGR1; FcgRI; FCRI; FcRIA; FLJ18345; FCGR1A; IGFR1; Fcr; Fcgr; FCE1A; FcERI; FcγRI; Fc γRI; Fcγ RI; Fc γ RI

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.