CD8 alpha/CD8A, His, Mouse
CD8 Alpha/CD8A, His, Mouse

The purity of CD8 alpha/CD8A, His, Mouse is greater than 95% as determined by SEC-HPLC.

CD8 Alpha/CD8A, His, Mouse

CD8 alpha/CD8A, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

CD8 alpha/CD8A, His, Mouse

CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.
Z04331
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Product Introduction
Species Mouse
Protein Construction
CD8 alpha/CD8A (Lys28-Tyr196）
Accession # P01731-1		 His
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 20 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 32-42 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS, (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • CD8 Alpha/CD8A, His, Mouse
    • CD8 Alpha/CD8A, His, Mouse

    The purity of CD8 alpha/CD8A, His, Mouse is greater than 95% as determined by SEC-HPLC.

  • CD8 Alpha/CD8A, His, Mouse
    • CD8 Alpha/CD8A, His, Mouse

    CD8 alpha/CD8A, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.
Synonyms CD8a; Lyt-2; CD8; Leu2; MAL; p32; CD8a molecule; OKT8 T-cell antigen

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.