CD27 Ligand/CD70 hFc Chimera, Mouse
CD27 Ligand/CD70 HFc Chimera, Mouse

Immobilized Mouse CD27, mFc Tag at 2 μg/ml (100 μL/well) on the plate. Dose response curve for CD27 Ligand/CD70 hFc Chimera, Mouse, hFc Tag with the EC50 of 20.4 ng/ml determined by ELISA.

CD27 Ligand/CD70 HFc Chimera, Mouse

The purity of CD27 Ligand/CD70 hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC.

CD27 Ligand/CD70 HFc Chimera, Mouse

CD27 Ligand/CD70 hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

CD27 Ligand/CD70 hFc Chimera, Mouse

CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
Z04306
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Product Introduction
Species Mouse
Protein Construction
hFc CD27 Ligand/CD70 (Ser45-Pro195)
Accession # O55237
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized Mouse CD27, mFc Tag at 2μg/ml (100μl/Well) on the plate can bind CD27 Ligand/CD70 hFc Chimera, Mouse. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 43.41 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 55-60 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 6.2).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • CD27 Ligand/CD70 HFc Chimera, Mouse
    • CD27 Ligand/CD70 HFc Chimera, Mouse

    Immobilized Mouse CD27, mFc Tag at 2 μg/ml (100 μL/well) on the plate. Dose response curve for CD27 Ligand/CD70 hFc Chimera, Mouse, hFc Tag with the EC50 of 20.4 ng/ml determined by ELISA.

  • CD27 Ligand/CD70 HFc Chimera, Mouse
    • CD27 Ligand/CD70 HFc Chimera, Mouse

    The purity of CD27 Ligand/CD70 hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC.

  • CD27 Ligand/CD70 HFc Chimera, Mouse
    • CD27 Ligand/CD70 HFc Chimera, Mouse

    CD27 Ligand/CD70 hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
Synonyms CD70 molecule; CD70; TNFSF7; CD27 Ligand; CD27-L; CD27LG; Ki-24 antigen; TNFSF7G

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.