CD30 Ligand/TNFSF8 mFc Chimera, Human
CD30 Ligand/TNFSF8 MFc Chimera, Human

Immobilized Human CD30, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for CD30 Ligand/TNFSF8 mFc Chimera, Human, mFc Tag with the EC50 of 8.5 ng/ml determined by ELISA.

CD30 Ligand/TNFSF8 MFc Chimera, Human

The purity of CD30 Ligand/TNFSF8 mFc Chimera, HumanCD30 Ligand/TNFSF8 mFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

CD30 Ligand/TNFSF8 MFc Chimera, Human

CD30 Ligand/TNFSF8 mFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

CD30 Ligand/TNFSF8 mFc Chimera, Human

CD30 ligand (CD30L)/TNFSF8 is a type II membrane protein belonging to the TNF superfamily. CD30L is expressed on the cell surface of activated T cells, B cells, and monocytes. The protein is also constitutively expressed on granulocytes and medullary thymic epithelial cells.CD30L is a cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.
Z04186
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Product Introduction
Species Human
Protein Construction
mFc (IgG2a） CD30 Ligand/TNFSF8 (Gln63-Asp234)
Accession # P32971-1
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 46.2 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 62-68 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • CD30 Ligand/TNFSF8 MFc Chimera, Human
    • CD30 Ligand/TNFSF8 MFc Chimera, Human

    Immobilized Human CD30, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for CD30 Ligand/TNFSF8 mFc Chimera, Human, mFc Tag with the EC50 of 8.5 ng/ml determined by ELISA.

  • CD30 Ligand/TNFSF8 MFc Chimera, Human
    • CD30 Ligand/TNFSF8 MFc Chimera, Human

    The purity of CD30 Ligand/TNFSF8 mFc Chimera, HumanCD30 Ligand/TNFSF8 mFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

  • CD30 Ligand/TNFSF8 MFc Chimera, Human
    • CD30 Ligand/TNFSF8 MFc Chimera, Human

    CD30 Ligand/TNFSF8 mFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background CD30 ligand (CD30L)/TNFSF8 is a type II membrane protein belonging to the TNF superfamily. CD30L is expressed on the cell surface of activated T cells, B cells, and monocytes. The protein is also constitutively expressed on granulocytes and medullary thymic epithelial cells.CD30L is a cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.
Synonyms CD153; CD30 Ligand; CD30L; CD30-L; CD30LGMGC138144; TNFSF8; CD30LG

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.