CD27 Ligand/CD70 Trimer, His, Human
CD27 Ligand/CD70 Trimer, His, Human

Immobilized CD27 Ligand/CD70 Trimer, His, Human, His Tag at 2 μg/ml (100 μL/well) on the plate. Dose response curve for Human CD27, hFc Tag with the EC50 of 11.8 ng/ml determined by ELISA.

CD27 Ligand/CD70 Trimer, His, Human

The purity of CD27 Ligand/CD70 Trimer, His, Human is greater than 95% as determined by SEC-HPLC.

CD27 Ligand/CD70 Trimer, His, Human

CD27 Ligand/CD70 Trimer, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

CD27 Ligand/CD70 Trimer, His, Human

CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
Z04180
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Product Introduction
Species Human
Protein Construction
His CD27 Ligand/CD70 Trimer (Leu50-Pro193)
Accession # P32970-1
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized CD27 Ligand/CD70 Trimer, His, Human at 2μg/ml (100μl/Well) on the plate can bind Human CD27, hFc Tag. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 51.8 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 62-65 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • CD27 Ligand/CD70 Trimer, His, Human
    • CD27 Ligand/CD70 Trimer, His, Human

    Immobilized CD27 Ligand/CD70 Trimer, His, Human, His Tag at 2 μg/ml (100 μL/well) on the plate. Dose response curve for Human CD27, hFc Tag with the EC50 of 11.8 ng/ml determined by ELISA.

  • CD27 Ligand/CD70 Trimer, His, Human
    • CD27 Ligand/CD70 Trimer, His, Human

    The purity of CD27 Ligand/CD70 Trimer, His, Human is greater than 95% as determined by SEC-HPLC.

  • CD27 Ligand/CD70 Trimer, His, Human
    • CD27 Ligand/CD70 Trimer, His, Human

    CD27 Ligand/CD70 Trimer, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
Synonyms CD70 molecule; CD70; TNFSF7; CD27 Ligand; CD27-L; CD27LG; Ki-24 antigen; TNFSF7G

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.