CD27/TNFRSF7 hFc Chimera, Cynomolgus/Rhesus macaque
CD27/TNFRSF7 HFc Chimera, Cynomolgus/Rhesus Macaque

Immobilized Cynomolgus CD27 Ligand, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for CD27/TNFRSF7 hFc Chimera, Cynomolgus/Rhesus macaque, hFc Tag with the EC50 of 18.0 ng/ml determined by ELISA.

CD27/TNFRSF7 HFc Chimera, Cynomolgus/Rhesus Macaque

The purity of CD27/TNFRSF7 hFc Chimera, Cynomolgus/Rhesus macaqueis greater than 95% as determined by SEC-HPLC.

CD27/TNFRSF7 HFc Chimera, Cynomolgus/Rhesus Macaque

CD27/TNFRSF7 hFc Chimera, Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

CD27/TNFRSF7 hFc Chimera, Cynomolgus/Rhesus macaque

CD27, also known as TNFRSF7, is an approximately 55 kDa transmembrane protein in the TNF receptor superfamily. It functions as a co‑stimulatory molecule that supports lymphocyte activation and survival. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.
Z04142
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Product Introduction
Species Cynomolgus/Rhesus macaque
Protein Construction
CD27/TNFRSF7 (Ala20-Arg191)
Accession # XP_005569963.1		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 46.5 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • CD27/TNFRSF7 HFc Chimera, Cynomolgus/Rhesus Macaque
    • CD27/TNFRSF7 HFc Chimera, Cynomolgus/Rhesus Macaque

    Immobilized Cynomolgus CD27 Ligand, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for CD27/TNFRSF7 hFc Chimera, Cynomolgus/Rhesus macaque, hFc Tag with the EC50 of 18.0 ng/ml determined by ELISA.

  • CD27/TNFRSF7 HFc Chimera, Cynomolgus/Rhesus Macaque
    • CD27/TNFRSF7 HFc Chimera, Cynomolgus/Rhesus Macaque

    The purity of CD27/TNFRSF7 hFc Chimera, Cynomolgus/Rhesus macaqueis greater than 95% as determined by SEC-HPLC.

  • CD27/TNFRSF7 HFc Chimera, Cynomolgus/Rhesus Macaque
    • CD27/TNFRSF7 HFc Chimera, Cynomolgus/Rhesus Macaque

    CD27/TNFRSF7 hFc Chimera, Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background CD27, also known as TNFRSF7, is an approximately 55 kDa transmembrane protein in the TNF receptor superfamily. It functions as a co‑stimulatory molecule that supports lymphocyte activation and survival. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.
Synonyms CD27 antigen; Tp55; TNFRSF7; S152; T14; S152. LPFS2; MGC20393; S152CD27L receptor

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.