CD27/TNFRSF7, His, Cynomolgus/Rhesus macaque
CD27/TNFRSF7, His, Cynomolgus/Rhesus Macaque

Immobilized CD27/TNFRSF7, His, Cynomolgus/Rhesus macaque, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human CD27 Ligand, hFc Tag with the EC50 of 22.2 ng/ml determined by ELISA.

CD27/TNFRSF7, His, Cynomolgus/Rhesus Macaque

The purity of CD27/TNFRSF7, His, Cynomolgus/Rhesus macaque is greater than 95% as determined by SEC-HPLC.

CD27/TNFRSF7, His, Cynomolgus/Rhesus Macaque

CD27/TNFRSF7, His, Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

CD27/TNFRSF7, His, Cynomolgus/Rhesus macaque

CD27, also known as TNFRSF7, is an approximately 55 kDa transmembrane protein in the TNF receptor superfamily. It functions as a co‑stimulatory molecule that supports lymphocyte activation and survival. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.
Z04113
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Product Introduction
Species Cynomolgus/Rhesus macaque
Protein Construction
CD27/TNFRSF7 (Thr21-Ile192）
Accession # XP_005569963.1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized CD27/TNFRSF7, His, Cynomolgus/Rhesus macaque at 1μg/ml (100μl/well) on the plate can bind Human CD27 Ligand, hFc Tag. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 20.41 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 42-52 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • CD27/TNFRSF7, His, Cynomolgus/Rhesus Macaque
    • CD27/TNFRSF7, His, Cynomolgus/Rhesus Macaque

    Immobilized CD27/TNFRSF7, His, Cynomolgus/Rhesus macaque, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human CD27 Ligand, hFc Tag with the EC50 of 22.2 ng/ml determined by ELISA.

  • CD27/TNFRSF7, His, Cynomolgus/Rhesus Macaque
    • CD27/TNFRSF7, His, Cynomolgus/Rhesus Macaque

    The purity of CD27/TNFRSF7, His, Cynomolgus/Rhesus macaque is greater than 95% as determined by SEC-HPLC.

  • CD27/TNFRSF7, His, Cynomolgus/Rhesus Macaque
    • CD27/TNFRSF7, His, Cynomolgus/Rhesus Macaque

    CD27/TNFRSF7, His, Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background CD27, also known as TNFRSF7, is an approximately 55 kDa transmembrane protein in the TNF receptor superfamily. It functions as a co‑stimulatory molecule that supports lymphocyte activation and survival. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.
Synonyms CD27 antigen; Tp55; TNFRSF7; S152; T14; S152. LPFS2

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.