CD28 mFc Chimera, Canine
CD28 MFc Chimera, Canine

The purity of CD28 mFc Chimera, Canine is greater than 95% as determined by SEC-HPLC.

CD28 MFc Chimera, Canine

CD28 mFc Chimera, Canine on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

CD28 mFc Chimera, Canine

CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
Z04104
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Product Introduction
Species Canine
Protein Construction
CD28 (Thr18-Pro153)
Accession # Q9GKP3		 mFc (IgG1)
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 41.6 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • CD28 MFc Chimera, Canine
    • CD28 MFc Chimera, Canine

    The purity of CD28 mFc Chimera, Canine is greater than 95% as determined by SEC-HPLC.

  • CD28 MFc Chimera, Canine
    • CD28 MFc Chimera, Canine

    CD28 mFc Chimera, Canine on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
Synonyms CD28 antigen (Tp44); CD28 molecule; CD28; MGC138290

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.