Immobilized FGFR3 beta (IIIb)[Biotin], His & Avi, Human, His Tag at 1 μg/ml (100 μl/Well) on streptavidin(5 μg/ml) precoated plate. Dose response curve for Anti-FGFR3 Antibody, hFc Tag with the EC50 of 2.3ng/ml determined by ELISA.
The purity of FGFR3 beta (IIIb)[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.
FGFR3 beta (IIIb)[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
FGFR3 beta (IIIb)[Biotin], His & Avi, Human
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis.
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