CD155/PVR hFc Chimera[Biotin], Avi, Human

CD155/PVR hFc Chimera[Biotin], Avi, Human

CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR.
Z04052
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Product Introduction
Species Human
Protein Construction
CD155/PVR (Trp21-Asn343)
Accession # P15151-1		 hFc Avi
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized CD155/PVR hFc Chimera[Biotin], Avi, Human at 5μg/ml (100μl/Well) on streptavidin (5μg/ml) precoated plate can bind Human TIGIT, His Tag. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 62.82 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 80-100 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Background
Target Background CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the 'poliovirus receptor,' or PVR.
Synonyms CD155; HVED; NECL5; Necl-5; nectin-like 5; PVR; PVS; Tage4; PVSFLJ25946; FLJ25946

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.