CD6, His, Human

CD6, His, Human

The cell surface glycoprotein CD6 is expressed on leukocytes and mediates T cell trafficking across endothelial cell barriers. CD6 is a lymphocyte surface co-receptor physically associated with the T-cell receptor (TCR)/CD3 complex at the center of the immunological synapse.
Z04027
¥61,625.00

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Product Introduction
Species Human
Protein Construction
CD6 (His18-Leu402)
Accession # NP_006716.3		 His
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized CD6, His, Human at 1μg/ml (100μl/well) on the plate can bind Human ALCAM, hFc Tag. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 42.14 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 70-90 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS，(pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Background
Target Background The cell surface glycoprotein CD6 is expressed on leukocytes and mediates T cell trafficking across endothelial cell barriers. CD6 is a lymphocyte surface co-receptor physically associated with the T-cell receptor (TCR)/CD3 complex at the center of the immunological synapse.
Synonyms CD6; TP120; T12

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.