VEGF R2/KDR mFc Chimera, Human

VEGF R2/KDR mFc Chimera, Human

Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis.
Z03966
¥54,375.00

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Product Introduction
Species Human
Protein Construction
VEGF R2/KDR (Ala20-Glu764)
Accession # P35968-1		 mFc (IgG1)
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Immobilized Human VEGF165 at 1 μg/ml (100μl/well) on the plate can bind VEGF R2/KDR mFc Chimera, Human (Cat.No.: Z03966)
Expression System HEK293
Theoretical Molecular Weight 110 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 150-200 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS, (pH 7.4).
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O more than 100 μg/ml.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Background
Target Background Vascular endothelial growth factor receptor 2 (VEGFR2) is one kind of tyrosine kinase receptors. VEGFR2 acts as a cell-surface receptor for VEGFA, VEGFB and PGF. It plays an important role in the development of embryonic vasculature, cell survival and cancer cell invasion. VEGFR2 is a key regulator of angiogenesis.
Synonyms CD309; KDR; VEGFR; VEGFR2; VEGFR-21; FLK1; KRD1; Ly73

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.