GUCY2C/Guanylyl cyclase C, His, Cynomolgus

GUCY2C/Guanylyl cyclase C, His, Cynomolgus

Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.
Z03914
¥70,688.00

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Product Introduction
Species Cynomolgus
Protein Construction
GUCY2C/Guanylyl cyclase C (Ser24-Gln430)
Accession # XP_005570270.1		 His
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Immobilized GUCY2C/Guanylyl cyclase C, His, Cynomolgus (Cat.No.: Z03914) at 5 μg/ml (100μl/Well) on the plate can bind Anti-GUCY2C Antibody, hFc Tag
Expression System HEK293
Theoretical Molecular Weight 47.2 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-75 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4 .
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O more than 100 μg/ml.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Background
Target Background Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.
Synonyms Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.