Immobilized Her3, His, Cynomolgus/Rhesus macaque at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 0.12 μg/ml determined by ELISA.

The purity of Her3, His, Cynomolgus/Rhesus macaque is greater than 95% as determined by SEC-HPLC.

Her3, His, Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Immobilized Her3, His,Cynomolgus/Rhesus macaque, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-HER3 Antibody, hFc Tag with the EC50 of 8.9 ng/ml determined by ELISA.

Her3, His,Cynomolgus/Rhesus macaque

Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).

Cat. No.	Z03909
Size	100 μg : Quote 500 μg : Quote Buy in bulk
Quantity
Price	¥61,559.00


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Product Introduction

Species

Cynomolgus/Rhesus macaque

Protein Construction

Her3 (Ser20-His641) Accession # XP_005571238.1/G7N7B1	His
N-term	C-term

Purity

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

Immobilized Her3, His,Cynomolgus/Rhesus macaque (Cat.No.: Z03909) at 1 μg/ml (100μl/Well) on the platecan bind Human NRG1 Beta 1, hFc Tag

Expression System

HEK293

Theoretical Molecular Weight

69.54 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 85-105 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4.

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O more than 100 μg/ml.

Storage & Stability

Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples

Immobilized Her3, His, Cynomolgus/Rhesus macaque at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 0.12 μg/ml determined by ELISA.

The purity of Her3, His, Cynomolgus/Rhesus macaque is greater than 95% as determined by SEC-HPLC.

Her3, His, Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Immobilized Her3, His,Cynomolgus/Rhesus macaque, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-HER3 Antibody, hFc Tag with the EC50 of 8.9 ng/ml determined by ELISA.

Background

Target Background	Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).
Synonyms	ErbB3; ErbB-3; HER3; HER3c-erbB-3; LCCS2; MDA-BF-1; MGC88033; p180-ErbB3; p45-sErbB3; p85-sErbB3; ERBB3

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.

Her3, His,Cynomolgus/Rhesus macaque

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