Her3/ErbB3[FITC], His & Avi, Human

Her3/ErbB3[FITC], His & Avi, Human

Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).
Z03908
¥139,563.00

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Product Introduction
Species Human
Protein Construction
Her3/ErbB3 (Ser20-Thr643)
Accession # P21860-1
His Avi
N-term C-term
Conjugate FITC
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Immobilized Her3/ErbB3[FITC], His & Avi, Human (Cat.No.: Z03908) at 5 μg/ml (100μl/Well) on the plate can bind Human NRG1 Beta 1, hFc Tag
Expression System HEK293
Theoretical Molecular Weight 71.6 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 72-75 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from a 0.22 μm filtered solution in HER-HM403F.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O more than 100 μg/ml.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Background
Target Background Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).
Synonyms ErbB3; ErbB-3; HER3; HER3c-erbB-3; LCCS2; MDA-BF-1; MGC88033; p180-ErbB3; p45-sErbB3; p85-sErbB3; ERBB3

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.