FAP[Biotin], His & Avi, Cynomolgus
FAP[Biotin], His & Avi, Cynomolgus

Immobilized FAP[Biotin], His & Avi, Cynomolgus at 0.5 μg/ml (100 μl/well) on the streptavidin precoated plate(5 μg/ml). Dose response curve for Anti-FAP Antibody, hFc Tag with the EC50 of 6.7 ng/ml determined by ELISA.

FAP[Biotin], His & Avi, Cynomolgus

FAP[Biotin], His & Avi, Cynomolgus on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.

FAP[Biotin], His & Avi, Cynomolgus

The purity of FAP[Biotin], His & Avi, Cynomolgus is greater than 95% as determined by SEC-HPLC.

FAP[Biotin], His & Avi, Cynomolgus

Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital in the malignant behaviors of cancer cells.
Z03896
¥149,234.00

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Product Introduction
Species Cynomolgus
Protein Construction
Avi His FAP (Leu26-Asp760)
Accession # XP_005573377
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Immobilized FAP[Biotin], His & Avi, Cynomolgus (Cat.No.: Z03896) at 0.5 μg/ml (100μl/Well) on the streptavidin precoated plate can bind Anti-FAP Antibody, hFc Tag
Expression System HEK293
Theoretical Molecular Weight 88 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 90-110 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in 20mM Tris, 500mM NaCl, 200mM L-arginine (pH 8.2).
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O more than 100 μg/ml.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • FAP[Biotin], His & Avi, Cynomolgus
    • FAP[Biotin], His & Avi, Cynomolgus

    Immobilized FAP[Biotin], His & Avi, Cynomolgus at 0.5 μg/ml (100 μl/well) on the streptavidin precoated plate(5 μg/ml). Dose response curve for Anti-FAP Antibody, hFc Tag with the EC50 of 6.7 ng/ml determined by ELISA.

  • FAP[Biotin], His & Avi, Cynomolgus
    • FAP[Biotin], His & Avi, Cynomolgus

    FAP[Biotin], His & Avi, Cynomolgus on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.

  • FAP[Biotin], His & Avi, Cynomolgus
    • FAP[Biotin], His & Avi, Cynomolgus

    The purity of FAP[Biotin], His & Avi, Cynomolgus is greater than 95% as determined by SEC-HPLC.


Background
Target Background Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital in the malignant behaviors of cancer cells.
Synonyms FAP; FAPalpha; SIMP; Seprase; APCE; DPPIV; DPPIVA; FAPA

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.