BCMA/TNFRSF17 hFc Chimera, Human
BCMA/TNFRSF17 HFc Chimera, Human

Immobilized Human APRIL (Trimer), His Tag at 0.1 μg/ml (100 μl/well) on the plate. Dose response curve for BCMA/TNFRSF17 hFc Chimera, Human, hFc Tag with the EC50 of 0.9 ng/ml determined by ELISA.

BCMA/TNFRSF17 HFc Chimera, Human

The purity of BCMA/TNFRSF17 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

BCMA/TNFRSF17 HFc Chimera, Human

BCMA/TNFRSF17 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

BCMA/TNFRSF17 hFc Chimera, Human

B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF).
Z03847
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Product Introduction
Species Human
Protein Construction
BCMA/TNFRSF17 (Met1-Ala54)
Accession # Q02223-1		 hFc
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Immobilized Human APRIL Trimer, His Tagat 0.1 μg/ml (100μl/well) on the plate can bind BCMA/TNFRSF17 hFc Chimera, Human (Cat.No.: Z03847).
Expression System HEK293
Theoretical Molecular Weight 31.4 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • BCMA/TNFRSF17 HFc Chimera, Human
    • BCMA/TNFRSF17 HFc Chimera, Human

    Immobilized Human APRIL (Trimer), His Tag at 0.1 μg/ml (100 μl/well) on the plate. Dose response curve for BCMA/TNFRSF17 hFc Chimera, Human, hFc Tag with the EC50 of 0.9 ng/ml determined by ELISA.

  • BCMA/TNFRSF17 HFc Chimera, Human
    • BCMA/TNFRSF17 HFc Chimera, Human

    The purity of BCMA/TNFRSF17 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

  • BCMA/TNFRSF17 HFc Chimera, Human
    • BCMA/TNFRSF17 HFc Chimera, Human

    BCMA/TNFRSF17 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background BCMA (B-cell maturation antigen), also called TNFRSF17, is encoded by the TNFRSF17 gene. It acts as a cell surface receptor of the TNF receptor superfamily. BCMA recognizes B-cell activating factor (BAFF). It interacts with the B-cell activating factor TNFSF13B.
Synonyms CD269; TNFRSF17; BCMA; BCM; TNFRSF13A

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.