TROP-2/TACSTD2, His, Mouse

TROP-2/TACSTD2, His, Mouse

Trop-2,also known as epithelial glycoprotein-1 antigen (EGP-1),is a protein that in humans is encoded by the TACSTD2 gene.Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
Z03843
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Product Introduction
Species Mouse
Protein Construction
TROP-2/TACSTD2 (Gln25-Gly270)
Accession # Q8BGV3.1		 His
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 28.8 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 48-55 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Background
Target Background Trop-2 (Tumor-associated calcium signal transducer 2) is also known as epithelial glycoprotein-1 antigen (EGP-1). It is encoded by the TACSTD2 gene. The mutations of Trop-2 gene cause an autosomal recessive disorder. Trop-2 causes cancer cell growth, proliferation, invasion, migration, and survival of cancer cells
Synonyms EGP1; EGP-1; TROP2; GA733-1; gp50; T16; TACSTD2; TROP-2; M1S1; TACD2

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.