TROP-2/TACSTD2 hFc Chimera, Human
TROP-2/TACSTD2 HFc Chimera, Human

Immobilized TROP-2/TACSTD2 hFc Chimera, Human, hFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-TROP-2 Antibody, hFc Tag with the EC50 of 6.3 ng/ml determined by ELISA.

TROP-2/TACSTD2 HFc Chimera, Human

The purity of TROP-2/TACSTD2 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

TROP-2/TACSTD2 HFc Chimera, Human

TROP-2/TACSTD2 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

TROP-2/TACSTD2 hFc Chimera, Human

Trop-2,also known as epithelial glycoprotein-1 antigen (EGP-1),is a protein that in humans is encoded by the TACSTD2 gene.Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
Z03840
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Product Introduction
Species Human
Protein Construction
TROP-2/TACSTD2 (His27-Thr274)
Accession # P09758		 hFc
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 54.6 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • TROP-2/TACSTD2 HFc Chimera, Human
    • TROP-2/TACSTD2 HFc Chimera, Human

    Immobilized TROP-2/TACSTD2 hFc Chimera, Human, hFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-TROP-2 Antibody, hFc Tag with the EC50 of 6.3 ng/ml determined by ELISA.

  • TROP-2/TACSTD2 HFc Chimera, Human
    • TROP-2/TACSTD2 HFc Chimera, Human

    The purity of TROP-2/TACSTD2 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

  • TROP-2/TACSTD2 HFc Chimera, Human
    • TROP-2/TACSTD2 HFc Chimera, Human

    TROP-2/TACSTD2 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Trop-2 (Tumor-associated calcium signal transducer 2) is also known as epithelial glycoprotein-1 antigen (EGP-1). It is encoded by the TACSTD2 gene. The mutations of Trop-2 gene cause an autosomal recessive disorder. Trop-2 causes cancer cell growth, proliferation, invasion, migration, and survival of cancer cells
Synonyms EGP1; EGP-1; TROP2; GA733-1; gp50; T16; TACSTD2; TROP-2; M1S1; TACD2

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.