CEACAM-6/CD66c[Biotin], His& Avi, Human
CEACAM-6/CD66c[Biotin], His& Avi, Human

The purity of CEACAM-6/CD66c[Biotin], His& Avi, Human is greater than 95% as determined by SEC-HPLC.

CEACAM-6/CD66c[Biotin], His& Avi, Human

CEACAM-6/CD66c[Biotin], His& Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

CEACAM-6/CD66c[Biotin], His& Avi, Human

Human CEACAM-8, His Tag immobilized on CM5 Chip can bind CEACAM-6/CD66c[Biotin], His& Avi, Human, His-Avi Tag with an affinity constant of 3.81 μM as determined in SPR assay (Biacore T200).

CEACAM-6/CD66c[Biotin], His& Avi, Human

Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) belongs to the human carcino-embryonic antigen (CEA) family. Numerous lines of studies have indicated that altered expression of CEACAM6 may have a role in carcinogenesis and development.
Z03837
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Product Introduction
Species Human
Protein Construction
CEACAM-6/CD66c (Lys35-Gly320)
Accession # P40199		 His Avi
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 34.1 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 55-75 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • CEACAM-6/CD66c[Biotin], His& Avi, Human
    • CEACAM-6/CD66c[Biotin], His& Avi, Human

    The purity of CEACAM-6/CD66c[Biotin], His& Avi, Human is greater than 95% as determined by SEC-HPLC.

  • CEACAM-6/CD66c[Biotin], His& Avi, Human
    • CEACAM-6/CD66c[Biotin], His& Avi, Human

    CEACAM-6/CD66c[Biotin], His& Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • CEACAM-6/CD66c[Biotin], His& Avi, Human
    • CEACAM-6/CD66c[Biotin], His& Avi, Human

    Human CEACAM-8, His Tag immobilized on CM5 Chip can bind CEACAM-6/CD66c[Biotin], His& Avi, Human, His-Avi Tag with an affinity constant of 3.81 μM as determined in SPR assay (Biacore T200).


Background
Target Background CEACAM6 (carcinoembryonic antigen-related cell adhesion molecule 6), is encoded by the human CEACAM6 gene. It plays a probable role in both cell-cell signaling and cell adhesion, promoting tumor progression, invasion and metastasis. It is upregulated in pancreatic adenocarcinoma, breast cancer and non-small cell lung cancer.
Synonyms CEACAM6; CD66c; CEAL; NCA; CEA

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.