Wnt-3a hFc Chimera, Human

Wnt-3a hFc Chimera, Human

Wnt-3a activates the canonical Wnt signaling pathway and is expressed in the dorsal midline region, playing a crucial role in spinal cord development. Additionally, it regulates autophagy, apoptosis, neuron regeneration, neurogenic inflammation, and axon regeneration. Wnt-3a promotes the beta-catenin/Tcf pathway, which can induce tumors and lead to cancer in specific cell populations. Moreover, it is widely used in cytokine for organoid construction.
Z03815
¥67,969.00

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Product Introduction
Species Human
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1 EU per μg by the LAL method.
Biological Activity Wnt-3a hFc Chimera, Human (Cat.No.: Z03815) can induce Topflash reporter activity in HEK293T human embryonic kidney cells.
Expression System HEK293
Theoretical Molecular Weight 58.50 kDa.
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-75 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the lyophilized product remains stable up to 6 months at -20 °C or below as supplied from date of receipt.-80°C for 3 months after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Background
Target Background Wnt-3a activates the canonical Wnt signaling pathway and is expressed in the dorsal midline region, playing a crucial role in spinal cord development. Additionally, it regulates autophagy, apoptosis, neuron regeneration, neurogenic inflammation, and axon regeneration. Wnt-3a promotes the beta-catenin/Tcf pathway, which can induce tumors and lead to cancer in specific cell populations. Moreover, it is widely used in cytokine for organoid construction.
Synonyms Wnt-3a; Wnt 3a; WNT3A protein; Wnt3a

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.