Siglec-2/CD22, hFc, Human
Siglec-2/CD22, HFc, Human

Immobilized Human Siglec2 at 0.5 μg/ml (100 μl/Well). Dose response curve for Biotinylated Anti-Siglec2 Ab with the EC50 of 0.2 μg/ml determined by ELISA.

Siglec-2/CD22, HFc, Human

Recombinant Siglec-2/CD22 on SDS-PAGE under reducing conditions. The purity is greater than 95%.

Siglec-2/CD22, HFc, Human

The purity of Siglec-2/CD22 is greater than 95% as determined by SEC-HPLC

Siglec-2/CD22, hFc, Human

CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice.
Z03643
¥39,875.00

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Product Introduction
Species Human
Protein Construction
Siglec-2/CD22 (Asp20-Arg687)
Accession # P20273		 hFc
N-term C-term
Purity > 95% as analyzed by SDS-PAGE
> 95% as analyzed by HPLC
Endotoxin Level ≤ 1 EU/μg of protein by LAL method
Biological Activity Immobilized Human Siglec2 at 0.5 μg/ml (100 μl/Well). Dose response curve for Biotinylated Anti-Siglec2 Ab with the EC50 of 0.2 μg/ml determined by ELISA.
Expression System Expi293
Apparent Molecular Weight 120~130 kDa, on SDS-PAGE under reducing conditions.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4. Normally 5 % trehalose is added as protectant before lyophilization.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Avoid repeated freeze-thaw cycles.

Examples
  • Siglec-2/CD22, HFc, Human
    • Siglec-2/CD22, HFc, Human

    Immobilized Human Siglec2 at 0.5 μg/ml (100 μl/Well). Dose response curve for Biotinylated Anti-Siglec2 Ab with the EC50 of 0.2 μg/ml determined by ELISA.

  • Siglec-2/CD22, HFc, Human
    • Siglec-2/CD22, HFc, Human

    Recombinant Siglec-2/CD22 on SDS-PAGE under reducing conditions. The purity is greater than 95%.

  • Siglec-2/CD22, HFc, Human
    • Siglec-2/CD22, HFc, Human

    The purity of Siglec-2/CD22 is greater than 95% as determined by SEC-HPLC


Background
Target Background CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice.
Synonyms CD22 molecule; CD22; Siglec2; Siglec-2;B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigenMGC130020; sialic acid binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2;  SIGLEC2FLJ22814; T-cell surface antigen Leu-14

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.