Immobilized Human Siglec2 at 0.5 μg/ml (100 μl/Well). Dose response curve for Biotinylated Anti-Siglec2 Ab with the EC50 of 0.2 μg/ml determined by ELISA.

Recombinant Siglec-2/CD22 on SDS-PAGE under reducing conditions. The purity is greater than 95%.

The purity of Siglec-2/CD22 is greater than 95% as determined by SEC-HPLC

Immobilized Siglec-2/CD22, hFc, Human, hFc Tag at 2 μg/ml(100 μL/well) on the plate. Dose response curve for Biotinylated Anti-Siglec-2 Antibody, hFc Tag with the EC50 of 14.9 ng/ml determined by ELISA.

The purity of Siglec-2/CD22, hFc, Human is greater than 95% as determined by SEC-HPLC

Siglec-2/CD22, hFc, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Siglec-2/CD22, hFc, Human

CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice.

Cat. No.	Z03643
Size	100 μg : Quote Buy in bulk
Quantity
Price	¥41,039.00


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Product Introduction

Species

Human

Protein Construction

Siglec-2/CD22 (Asp20-Arg687) Accession # P20273	hFc
N-term	C-term

Purity

> 95% as analyzed by SDS-PAGE
> 95% as analyzed by HPLC

Endotoxin Level

≤ 1 EU/μg of protein by LAL method

Biological Activity

Immobilized Human Siglec2 at 0.5 μg/ml (100 μl/Well). Dose response curve for Biotinylated Anti-Siglec2 Ab with the EC₅₀ of 0.2 μg/ml determined by ELISA.

Expression System

Expi293

Apparent Molecular Weight

120~130 kDa, on SDS-PAGE under reducing conditions.

Formulation

Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4. Normally 5 % trehalose is added as protectant before lyophilization.

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.

Storage & Stability

Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Avoid repeated freeze-thaw cycles.

Examples

Immobilized Human Siglec2 at 0.5 μg/ml (100 μl/Well). Dose response curve for Biotinylated Anti-Siglec2 Ab with the EC50 of 0.2 μg/ml determined by ELISA.

Recombinant Siglec-2/CD22 on SDS-PAGE under reducing conditions. The purity is greater than 95%.

The purity of Siglec-2/CD22 is greater than 95% as determined by SEC-HPLC

The purity of Siglec-2/CD22, hFc, Human is greater than 95% as determined by SEC-HPLC

Siglec-2/CD22, hFc, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Background

Target Background	CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice.
Synonyms	CD22 molecule; CD22; Siglec2; Siglec-2;B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigenMGC130020; sialic acid binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2; SIGLEC2FLJ22814; T-cell surface antigen Leu-14

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.

Siglec-2/CD22, hFc, Human

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