Siglec-2/CD22, hFc, Human
Siglec-2/CD22, HFc, Human

Immobilized Human Siglec2 at 0.5 μg/ml (100 μl/Well). Dose response curve for Biotinylated Anti-Siglec2 Ab with the EC50 of 0.2 μg/ml determined by ELISA.

Siglec-2/CD22, HFc, Human

Immobilized Siglec-2/CD22, hFc, Human, hFc Tag at 2 μg/ml(100 μL/well) on the plate. Dose response curve for Biotinylated Anti-Siglec-2 Antibody, hFc Tag with the EC50 of 14.9 ng/ml determined by ELISA.

Siglec-2/CD22, HFc, Human

Siglec-2/CD22, hFc, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Siglec-2/CD22, hFc, Human

CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice.
Z03643
¥41,039.00

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Product Introduction
Species Human
Protein Construction
Siglec-2/CD22 (Asp20-Arg687)
Accession # P20273		 hFc
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level ≤ 1 EU/μg of protein by LAL method
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 101.9 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 120-130 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O more than 100 μg/ml.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • Siglec-2/CD22, HFc, Human
    • Siglec-2/CD22, HFc, Human

    Immobilized Human Siglec2 at 0.5 μg/ml (100 μl/Well). Dose response curve for Biotinylated Anti-Siglec2 Ab with the EC50 of 0.2 μg/ml determined by ELISA.

  • Siglec-2/CD22, HFc, Human
    • Siglec-2/CD22, HFc, Human

    Immobilized Siglec-2/CD22, hFc, Human, hFc Tag at 2 μg/ml(100 μL/well) on the plate. Dose response curve for Biotinylated Anti-Siglec-2 Antibody, hFc Tag with the EC50 of 14.9 ng/ml determined by ELISA.

  • Siglec-2/CD22, HFc, Human
    • Siglec-2/CD22, HFc, Human

    Siglec-2/CD22, hFc, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice.
Synonyms CD22 molecule; CD22; Siglec2; Siglec-2;B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigenMGC130020; sialic acid binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2;  SIGLEC2FLJ22814; T-cell surface antigen Leu-14

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.