ROR1, hFc, Human
ROR1, HFc, Human

Recombinant human ROR1 Protein on SDS-PAGE under reducing conditions, the purity is greater than 95%.

ROR1, HFc, Human

The purity of Recombinant human ROR1 Protein is greater than 95% as determined by SEC-HPLC.

ROR1, hFc, Human

ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1), is a member of the ROR family within the receptor tyrosine kinases (RTK) superfamily. Two ROR family members (ROR1 and ROR2) have been identified and are characterized by the intracellular tyrosine kinase domains, highly related to those of the Trk-family receptor tyrosine kinases, and by the extracellular Frizzled-like cysteine-rich domains and kringle domains, which are common to receptors of the Wnt family members.
Z03640
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Product Introduction
Species Human
Protein Construction
ROR1 (Gln30-Glu403)
Accession # Q01973-1		 hFc
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Endotoxin Level ≤ 1 EU/μg of protein by LAL method
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized ROR1, hFc, Human at 1μg/ml (100μl/well) on the plate can bind Biotinylated Anti­ROR1 Antibody, hFc Tag. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 68.8 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 80-100 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O more than 100 μg/ml.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • ROR1, HFc, Human
    • ROR1, HFc, Human

    Recombinant human ROR1 Protein on SDS-PAGE under reducing conditions, the purity is greater than 95%.

  • ROR1, HFc, Human
    • ROR1, HFc, Human

    The purity of Recombinant human ROR1 Protein is greater than 95% as determined by SEC-HPLC.


Background
Target Background ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1), is a member of the ROR family within the receptor tyrosine kinases (RTK) superfamily. Two ROR family members (ROR1 and ROR2) have been identified and are characterized by the intracellular tyrosine kinase domains, highly related to those of the Trk-family receptor tyrosine kinases, and by the extracellular Frizzled-like cysteine-rich domains and kringle domains, which are common to receptors of the Wnt family members.
Synonyms EC 2.7.10.1; MGC99659; neurotrophic tyrosine kinase receptor-related 1; Neurotrophic tyrosine kinase, receptor-related 1; NTRKR1; NTRKR1dJ537F10.1; receptor tyrosine kinase-like orphan receptor 1; ROR1; tyrosine-protein kinase transmembrane receptor ROR1

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.