CLDN18.2, His, Human
CLDN18.2, His, Human

Lane BSA: 2 μg BSA
Lane R: 2 μg CLDN18.2, reducing(R), no heat treatment before loading
> 90% as analyzed by SDS-PAGE

CLDN18.2, His, Human

Immobilized CLDN18.2, His, Human (Cat. No.: Z03504) at 1μg/mL (100μl/well). Dose response curve for anti-Claudin 18.2 Antibody with the EC50 of 13.75ng/mL determined by ELISA.

CLDN18.2, His, Human

Claudin-18 is a protein that in humans is encoded by the CLDN18 gene. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. The Expression of Isoform A2 (CLDN18.2) is restricted to the stomach mucosa where it is predominantly observed in the epithelial cells of the pit region and the base of the gastric glands including exocrine and endocrine cells (at protein level). CLDN18.2 is founded to be abundant in gastric tumors, Experimental antibody IMAB362 targets Claudin 18.2 to help treat gastric cancers.
Z03504
¥39,875.00

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Product Introduction
Species Human
Protein Construction
Poly-His CLDN18.2 (Met1-Lys207)
Accession # P56856-2
N-term C-term
Purity > 80% as analyzed by SDS-PAGE
Biological Activity Immobilized CLDN18.2, His, Human (Cat. No.: Z03504) at 1.0 μg/mL (100μl/well). Dose response curve for anti-Claudin 18.2 Antibody with the EC50 of 13.75ng/mL determined by ELISA.
Expression System Insect Cells
Theoretical Molecular Weight 27.7 kDa
Formulation Supplied as a solution in 50 mM Hepes, 500 mM NaCl, 10% glycerol, 0.2% DDM, 0.04% CHS, pH 7.5.
Concentration Please refer to the COA for the specific lot.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at -80°C. Please avoid repeated freeze-thaw cycles.

Examples
  • CLDN18.2, His, Human
    • CLDN18.2, His, Human

    Lane BSA: 2 μg BSA
    Lane R: 2 μg CLDN18.2, reducing(R), no heat treatment before loading
    > 90% as analyzed by SDS-PAGE

  • CLDN18.2, His, Human
    • CLDN18.2, His, Human

    Immobilized CLDN18.2, His, Human (Cat. No.: Z03504) at 1μg/mL (100μl/well). Dose response curve for anti-Claudin 18.2 Antibody with the EC50 of 13.75ng/mL determined by ELISA.


Background
Target Background Claudin-18 is a protein that in humans is encoded by the CLDN18 gene. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. The Expression of Isoform A2 (CLDN18.2) is restricted to the stomach mucosa where it is predominantly observed in the epithelial cells of the pit region and the base of the gastric glands including exocrine and endocrine cells (at protein level). CLDN18.2 is founded to be abundant in gastric tumors, Experimental antibody IMAB362 targets Claudin 18.2 to help treat gastric cancers.
Synonyms Claudin-18; CLDN18; SFTA5; SFTPJ; claudin 18

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.