リコンビナントタンパク質＿精製したリコンビナントタンパク質 » リコンビナントサイトカイン-免疫活性タンパク質 » IL-2, Human (HEK 293-expressed)
IL-2, Human

ED₅₀< 2ng/ml, measured in a cell proliferation assay using CTLL-2 cells.

IL-2, Human

GenScript product showed equal activity compared to competitor P

IL-2, Human

Manufacturing under ISO:13485 QMS is available. Request a Quote

Interleukin-2 (IL-2) is a Oglycosylated, four α-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes.
Z03074
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Product Introduction
Species Human
Protein Construction
IL-2 (Ala21-Thr153)
Accession # P60568
Purity > 95% as analyzed by SDS-PAGE
Endotoxin Level < 0.2 EU/μg of protein by gel clotting method
Biological Activity ED50 < 2.0 ng/ml, measured in a cell proliferation assay using CTLL-2 cells.
Expression System HEK 293
Apparent Molecular Weight 15~16 kDa, on SDS-PAGE under reducing conditions.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

Examples
  • IL-2, Human
    • IL-2, Human

    ED₅₀< 2ng/ml, measured in a cell proliferation assay using CTLL-2 cells.

  • IL-2, Human
    • IL-2, Human

    GenScript product showed equal activity compared to competitor P


Background
Target Background Interleukin-2 (IL-2) is a Oglycosylated, four α-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes.
Synonyms IL2; IL-2; TCGF; lymphokine; interleukin 2

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.