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PTH (1-84aa), Human

Lane 1: 2 μg of PTH (1-84aa), Human, non-reducing (NR)
Lane 2: 2 μg of PTH (1-84aa), Human, reducing (R)
> 95% as analyzed by SDS-PAGE

PTH (1-84aa), Human

Parathyroid Hormone (PTH) is the most important endocrine regulator of calcium and phosphorus con- centration in extracellular fluid. Parathyroid Hormone (PTH) is secreted from cells of the parathyroid glands and finds Parathyroid Hormone’s major target cells in bone and kidney. Like most other protein hormones, Parathyroid Hormone (PTH) is synthesized as a preprohormone. After intracellular processing, the mature hormone is packaged within the Golgi into secretory vesicles, the secreted into blood by exocytosis. Parathyroid Hormone (PTH) is secreted as a linear protein of 84 amino acids. Recombinant Human Parathyroid Hormone (PTH) produced in E. coli is a single, non-glycosylated, polypeptide chain containing 84 amino acids.
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Product Introduction
Species Human
Protein Construction
PTH (Ser32-Gln115)
Accession # P01270
Purity > 95% as analyzed by SDS-PAGE
Endotoxin Level < 1 EU/μg of protein by LAL method
Expression System E. coli
Theoretical Molecular Weight ~9.4 kDa
Apparent Molecular Weight ~14 kDa, on SDS-PAGE under non-reducing conditions.
Formulation Lyophilized from a 0.2 μm filtered solution of 10mM HAc-NaAc, 150mM NaCl, 5% Mannitol, pH 4.0.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.

Examples
  • PTH (1-84aa), Human
    • PTH (1-84aa), Human

    Lane 1: 2 μg of PTH (1-84aa), Human, non-reducing (NR)
    Lane 2: 2 μg of PTH (1-84aa), Human, reducing (R)
    > 95% as analyzed by SDS-PAGE


Background
Target Background Parathyroid Hormone (PTH) is the most important endocrine regulator of calcium and phosphorus con- centration in extracellular fluid. Parathyroid Hormone (PTH) is secreted from cells of the parathyroid glands and finds Parathyroid Hormone’s major target cells in bone and kidney. Like most other protein hormones, Parathyroid Hormone (PTH) is synthesized as a preprohormone. After intracellular processing, the mature hormone is packaged within the Golgi into secretory vesicles, the secreted into blood by exocytosis. Parathyroid Hormone (PTH) is secreted as a linear protein of 84 amino acids. Recombinant Human Parathyroid Hormone (PTH) produced in E. coli is a single, non-glycosylated, polypeptide chain containing 84 amino acids.
Synonyms Parathyroid Hormone

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.