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Protein G

Protein G, a cell surface protein of group G streptococci, is a Type III Fc receptor that binds to the Fc region of IgG by a non-immune mechanism similar to that of protein A from Staphylococcus aureus. This product contains three IgG binding domains, but its albumin-binding region has been removed. Additionally, His-tag and cysteine have been added to N- and C-termini, respectively, to facilitate purification and conjugation. This does not affect the protein's ability to bind to IgG.
Z02007
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Product Introduction
Purity This product is chromatographically purified and shows predominantly a single band by SDS-PAGE.
Focusing: pI of 4.69
Concentration 5 mg/ml before lyophilization


Background
Target Background Protein G, a cell surface protein of group G streptococci, is a Type III Fc receptor that binds to the Fc region of IgG by a non-immune mechanism similar to that of protein A from Staphylococcus aureus. This product contains three IgG binding domains, but its albumin-binding region has been removed. Additionally, His-tag and cysteine have been added to N- and C-termini, respectively, to facilitate purification and conjugation. This does not affect the protein's ability to bind to IgG.
Synonyms Protein G; G Protein

Applications
GenScript Protein G is suitable for use as antigen, as a control or standard in assays, for conjugation, and most other immunological methods.