GS-PepFirming™ Acetyl Hexapeptide-1

GS-PepFirming™ Acetyl Hexapeptide-1

Acetyl hexapeptide-1 is a botulinum toxin-like peptide obtained by in-silico design. It is widely used in anti-wrinkle products with higher activity and lower side effects.
RP30144
¥3,915,022.00

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Overview
Description Acetyl hexapeptide-1 is a botulinum toxin-like peptide obtained by in-silico design. It is widely used in anti-wrinkle products with higher activity and lower side effects.
Molecular Formula C43H59N13O7
Molecular Weight 870.0

Properties
Purity >95%
Form Lyophilized
Storage Store at -20°C. Keep tightly closed. Store in a cool dry place.
Note Processing and Dosage: The peptide can be incorporated at a temperature below 40℃ during the final stage of cosmetic manufacturing. It is recommended that 5 to 5000 ppm of the powder is present in the final formulation in order to obtain significant activity.

Applications
Acetyl hexapeptide-1 competing with specific sequences located in the surface of interaction between Munc18 and Syntaxin -1 allows an interference or inhibition of said complex Munc18-Syntaxin-1 and, hence an inhibition of neurotransmitter release. If the SNARE complex is slightly destabilized, the vesicle cannot release neurotransmitters efficiently and therefore muscle contraction is attenuated, preventing the formation of lines and wrinkles. It can be incorporated in cosmetic formulations such as emulsions, gels, essence, eye cream, etc., where removal of the deep lines or wrinkles in the forehead or around the eye area is desired.