安定細胞株製品 » Mouse Recombinant VISTA Stable Cell Line
CHO-K1/Mouse VISTA Stable Cell Line

FACS analysis of mouse VISTA expression in CHO-K1 cells.

CHO-K1/Mouse VISTA Stable Cell Line

V-domain Ig suppressor of T cell activation (VISTA) is a potent negative regulator of T-cell function that is expressed on hematopoietic cells. VISTA levels are heightened within the tumor microenvironment, in which its blockade can enhance antitumor immune responses in mice. In humans, blockade of the related programmed cell death 1 (PD-1) pathway has shown great potential in clinical immunotherapy trials.
M00633
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Description

V-domain Ig suppressor of T cell activation (VISTA) is a potent negative regulator of T-cell function that is expressed on hematopoietic cells. VISTA levels are heightened within the tumor microenvironment, in which its blockade can enhance antitumor immune responses in mice. In humans, blockade of the related programmed cell death 1 (PD-1) pathway has shown great potential in clinical immunotherapy trials.
Synonyms

Dies1; PD-1H; VISTA; 4632428N05Rik

Product Introduction
Stability 15 passages
Storage Liquid nitrogen immediately upon receiving

Culture Conditions
Culture Medium F12K, 10% FBS, 8 μg/ml Puromycin
Freeze Medium-DATA 95% complete growth medium, 5% DMSO

Examples
  • CHO-K1/Mouse VISTA Stable Cell Line
    • CHO-K1/Mouse VISTA Stable Cell Line

    FACS analysis of mouse VISTA expression in CHO-K1 cells.