Mouse Recombinant Adenosine A2A Receptor Stable Cell Line
CHO-K1/mouse ADORA2A Stable Cell Line

Dose dependent stimulation of intracellular cAMP mobilization upon treatment with NECA. The EC50 of NECA on CHO-K1/mouse ADORA2A cells was 9.57 nM.

CHO-K1/mouse ADORA2A Stable Cell Line

CHO-K1/mouse ADORA2A Stable Cell Line

The adenosine receptors ADORA2A are Gs-coupled GPCRs expressed in the thymus gland, heart, lung, kidney, brain, platelets, spleen and leukocytes. ADORA2A down-regulates chemokine receptor function and inhibits platelet aggregation. ADORA2A antagonists may be useful as therapy for Parkinson's disease.
M00575
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Description

The adenosine receptors ADORA2A are Gs-coupled GPCRs expressed in the thymus gland, heart, lung, kidney, brain, platelets, spleen and leukocytes. ADORA2A down-regulates chemokine receptor function and inhibits platelet aggregation. ADORA2A antagonists may be useful as therapy for Parkinson's disease.
Synonyms

RDC8; A2-AR; adenosine receptor A2a

Overview
Applications Functional assay for mouse ADORA2A receptor

Product Introduction
Storage Liquid nitrogen immediately upon delivery
Species mouse
Stability 16 passages

Culture Conditions
Freeze Medium 95% complete growth medium, 5% DMSO
Culture Medium F-12K, 10% FBS, 450 μg/ml Zeocin

Examples
  • CHO-K1/mouse ADORA2A Stable Cell Line
    • CHO-K1/mouse ADORA2A Stable Cell Line

    Dose dependent stimulation of intracellular cAMP mobilization upon treatment with NECA. The EC50 of NECA on CHO-K1/mouse ADORA2A cells was 9.57 nM.

  • CHO-K1/mouse ADORA2A Stable Cell Line
    • CHO-K1/mouse ADORA2A Stable Cell Line