安定細胞株製品 » Cyno Recombinant PD-L1 Stable Cell Line
CHO-K1/cyno PD-L1 Stable Cell Line

Flow cytometry analysis of cyno PD-L1 expression in CHO-K1/cyno PD-L1 cells.

CHO-K1/cyno PD-L1 Stable Cell Line

Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene. The formation of PD-1 receptor / PD-L1 or B7.1 receptor /PD-L1 ligand complex transmits an inhibitory signal which reduces the proliferation of these CD8+ T cells at the lymph nodes. Supplementary to that PD-1 is also able to control the accumulation of foreign antigen specific T cells in the lymph nodes through apoptosis which is further mediated by a lower regulation of the gene Bcl-2.
M00573
¥1,613,997.00

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Description

Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene. The formation of PD-1 receptor / PD-L1 or B7.1 receptor /PD-L1 ligand complex transmits an inhibitory signal which reduces the proliferation of these CD8+ T cells at the lymph nodes. Supplementary to that PD-1 is also able to control the accumulation of foreign antigen specific T cells in the lymph nodes through apoptosis which is further mediated by a lower regulation of the gene Bcl-2.
Synonyms

CD274, B7-H, B7H1, PDCD1L1, PDCD1LG1, PDL1, CD274 molecule, Programmed cell death 1 ligand 1

Overview
Applications Binding assay or use as immunogen

Product Introduction
Storage Liquid nitrogen immediately upon receipt
Species cyno
Stability 15 passages

Culture Conditions
Freeze Medium 95% complete growth medium, 5% DMSO
Culture Medium F12K, 10% FBS, 6 μg/ml Puromycin

Examples
  • CHO-K1/cyno PD-L1 Stable Cell Line
    • CHO-K1/cyno PD-L1 Stable Cell Line

    Flow cytometry analysis of cyno PD-L1 expression in CHO-K1/cyno PD-L1 cells.