安定細胞株製品 » Human Recombinant SST1 Somatostatin Receptor Stable Cell Line
CHO-K1/SST1/Gqi5 Stable Cell Line

CHO-K1/SST1/Gqi5 Stable Cell Line

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SST1 receptor is a Gi/Go-coupled GPCR which is expressed in pancreatic islets, pituitary, Cerebellum (Purkinje cells), frontal cortex (pyramidal cells), hippocampus (CA1-4 subfields and some granule cells of the dentate gyrus). It inhibits cAMP accumulation and stimulates tyrosine phosphatase activity, it also can antiproliferation.GenScript's SST1-expressing stable cell line was made in CHO-K1/Gqi5 host cell and optimized for calcium assays.
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Description

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SST1 receptor is a Gi/Go-coupled GPCR which is expressed in pancreatic islets, pituitary, Cerebellum (Purkinje cells), frontal cortex (pyramidal cells), hippocampus (CA1-4 subfields and some granule cells of the dentate gyrus). It inhibits cAMP accumulation and stimulates tyrosine phosphatase activity, it also can antiproliferation.
GenScript's SST1-expressing stable cell line was made in CHO-K1/Gqi5 host cell and optimized for calcium assays.
Synonyms

sst1 receptor, SSTR1, SRIF2, SRIF2A, Gpcrrna, RNGPCRRNA, SRIF-2, SS-1-R, SS1-R, SS1R, Somatostatin receptor subtype 1, somatostatin receptor 1, somatostatin receptor type 1, sst1, Smstr-1, Smstr1

Overview
Applications Functional assay for SST1 receptor

Product Introduction
Storage Liquid nitrogen immediately upon delivery
Species Human

Culture Conditions
Freeze Medium 45% culture medium, 45% FBS (Cat. #10099-141, Gibco), 10% DMSO (Cat. #D2650, Sigma)
Culture Medium Ham’s F-12K (Kaighn’s), 10% FBS, 200 μg/ml Zeocin (Cat. #R250-01, Life Technologies), 100 μg/ml Hygromycin B (Cat. #10687010, Invitrogen)

Examples
  • CHO-K1/SST1/Gqi5 Stable Cell Line
    • CHO-K1/SST1/Gqi5 Stable Cell Line