安定細胞株製品 » Human Recombinant 5-HT4 Serotonin Receptor Stable Cell Line

CHO-K1/5-HT4/Gα15 Stable Cell Line

*This product has been discontinued!*
5-HT4 is a human serotonin G protein-coupled receptor. Several studies suggested that intact 5-HT systems are important determinants of sensitivity and/or tolerance to ethanol-induce ataxia hypothermia. Attenuated response to stress and novelty and hypersensitivity to seizures in 5-HT receptor knock-out mice. Neuropsychiatric disorders such as anxiety, depression, migraine, vasospasm and epilepsy may involve different subtypes of the 5-HT receptor.
M00444
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Description

5-HT4 is a human serotonin G protein-coupled receptor. Several studies suggested that intact 5-HT systems are important determinants of sensitivity and/or tolerance to ethanol-induce ataxia hypothermia. Attenuated response to stress and novelty and hypersensitivity to seizures in 5-HT receptor knock-out mice. Neuropsychiatric disorders such as anxiety, depression, migraine, vasospasm and epilepsy may involve different subtypes of the 5-HT receptor.
Synonyms

5-HT4 receptor, 5-HT4, 5-hydroxytryptamine (serotonin) receptor 4, 5-HT-4, 5-HT4 receptor (two splicing variants L and S), 5-hydroxytryptamine receptor 4, serotonin receptor 4, 5 hydroxytryptamine (serotonin) receptor 4

Product Introduction
Storage Liquid nitrogen immediately upon delivery

Culture Conditions
Culture Medium Ham’s F-12K (Kaighn’s), 10% FBS, 400 μg/ml G418 (Cat. #10131-035, Gibco), 200 μg/ml Hygromycin B (Cat. #10687010, Invitrogen)
Freeze Medium-DATA 45% culture medium, 45% FBS (Cat. #10099-141, Gibco), 10% DMSO (Cat. #D2650, Sigma)