安定細胞株製品 » Human Recombinant Adenosine A1 Receptor Stable Cell Line

HEK293/ADORA1/Gα15 Stable Cell Line

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ADORA1 is a receptor for adenosine. It is demonstrated that the ADORA1 receptor is ubiquitous throughout the entire body. Activation of ADORA1 elicits an inhibition of adenylate cyclase and therefore a decrease in the cAMP concentration. ADORA1 receptors are implicated in sleep promotion by inhibiting wake promoting cholinergic neurons in the basal forebrain. Adenosine antagonists are widely used in neonatal medicine.
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Description

ADORA1 is a receptor for adenosine. It is demonstrated that the ADORA1 receptor is ubiquitous throughout the entire body. Activation of ADORA1 elicits an inhibition of adenylate cyclase and therefore a decrease in the cAMP concentration. ADORA1 receptors are implicated in sleep promotion by inhibiting wake promoting cholinergic neurons in the basal forebrain. Adenosine antagonists are widely used in neonatal medicine.

Synonyms

A1 receptor, Ri, RDC7, adenosine A1 receptor , A1AR, A1R, A1-AR, AA1R, Ri

Overview
Applications Functional assay for ADORA1 receptor

Product Introduction
Storage Liquid nitrogen immediately upon delivery
Species Human

Culture Conditions
Freeze Medium 45% culture medium, 45% FBS, 10% DMSO
Culture Medium DMEM, 10% FBS, 100 μg/ml Hygromycin B, 200 μg/ml Zeocin