Gene Symbol | acp2 |
Entrez Gene ID | 779653 |
Full Name | acid phosphatase 2, lysosomal |
General protein information |
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Gene Type | protein-coding |
Organism | Xenopus tropicalis(tropical clawed frog) |
Summary | The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. [provided by RefSeq, Oct 2017]. |