selenon cDNA ORF clone, Xenopus tropicalis(tropical clawed frog)

Gene
Clones
gRNAs

Summary

Gene Symbol	selenon
Entrez Gene ID	394859
Full Name	selenoprotein N
Synonyms	mdsr1,rsmd1,rss,sepn1
General protein information	Preferred Names selenoprotein N Names selenoprotein N selN selenoprotein N, 1
Gene Type	protein-coding
Organism	Xenopus tropicalis(tropical clawed frog)
Summary	This gene encodes a glycoprotein that is localized in the endoplasmic reticulum. It plays an important role in cell protection against oxidative stress, and in the regulation of redox-related calcium homeostasis. Mutations in the orthologous gene in human are associated with early onset muscle disorders, referred to as SEPN1-related myopathy. Studies in other species also suggest an important role for this gene in muscle development and differentiation during early development. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. A second stop-codon redefinition element (SRE) adjacent to the UGA codon has been identified in this gene (PMID:15791204). SRE is a phylogenetically conserved stem-loop structure that stimulates readthrough at the UGA codon, and augments the Sec insertion efficiency by SECIS. [provided by RefSeq, Dec 2016].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001077433.2	NP_001070901.1	selenoprotein N
NM_001077433.3	NP_001070901.1	selenoprotein N

Pathways from BioSystems

Homologies

	SEPN1	XP_002802303.1
Danio rerio (zebrafish)	sepn1	NP_001004294.4
Xenopus tropicalis (tropical clawed frog)	sepn1	NP_001070901.1
Rattus norvegicus (Norway rat)	Sepn1	XP_006239194.1
Gallus gallus (chicken)	SEPN1	NP_001108444.1
Bos taurus (cattle)	SEPN1	NP_001108448.1
Mus musculus (house mouse)	Sepn1	NP_083376.2
Homo sapiens (human)	SEPN1	NP_996809.1
Pan troglodytes (chimpanzee)	SEPN1	XP_003307954.2
Canis lupus familiaris (dog)	SEPN1	NP_001108447.1

Gene Ontology
Bibliography

Related articles in PubMed

Selenoprotein Gene Nomenclature.
Gladyshev VN, Arn?r ES, Berry MJ, Brigelius-Floh? R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L, Conrad M, Copeland PR, Diamond AM, Driscoll DM, Ferreiro A, Floh? L, Green FR, Guig? R, Handy DE, Hatfield DL, Hesketh J, Hoffmann PR, Holmgren A, Hondal RJ, Howard MT, Huang K, Kim HY, Kim IY, K?hrle J, Krol A, Kryukov GV, Lee BJ, Lee BC, Lei XG, Liu Q, Lescure A, Lobanov AV, Loscalzo J, Maiorino M, Mariotti M, Sandeep Prabhu K, Rayman MP, Rozovsky S, Salinas G, Schmidt EE, Schomburg L, Schweizer U, Simonovi? M, Sunde RA, Tsuji PA, Tweedie S, Ursini F, Whanger PD, Zhang Y
The Journal of biological chemistry291(46)24036-24040(2016 Nov)

Composition and evolution of the vertebrate and mammalian selenoproteomes.
Mariotti M, Ridge PG, Zhang Y, Lobanov AV, Pringle TH, Guigo R, Hatfield DL, Gladyshev VN
PloS one7(3)e33066(2012)

Recoding elements located adjacent to a subset of eukaryal selenocysteine-specifying UGA codons.
Howard MT, Aggarwal G, Anderson CB, Khatri S, Flanigan KM, Atkins JF
The EMBO journal24(8)1596-607(2005 Apr)

Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative.
Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW, Richardson P
Developmental dynamics : an official publication of the American Association of Anatomists225(4)384-91(2002 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following selenon gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the selenon cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OXa00620	NM_001077433.3 Latest version!	Xenopus tropicalis selenoprotein N (selenon), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
View Old Accession Versions >>
OXa00620	NM_001077433.2	Xenopus tropicalis selenoprotein N (selenon), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

selenon ( NM_001077433.2 ) cDNA ORF clone, Xenopus tropicalis(tropical clawed frog) -> NP_001070901.1 Xenopus tropicalis selenoprotein N (selenon), mRNA.

Price & Availability↑

CloneID	OXa00620
Clone ID Related Accession (Same CDS sequence)	NM_001077433.2 , NM_001077433.3
Accession Version	NM_001077433.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1689bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-23
Organism	Xenopus tropicalis(Tropical clawed frog)
Product	selenoprotein N
Comment	REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AAMC03038390.1. On Dec 29, 2016 this sequence version replaced NM_001077433.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: CR566474.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1696413, SAMEA1696417 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCAGCAG ATCTTCGAAA AAGAAAAAAA GACACCACTG CTGACAATGA TGCCCCACAG 
GAAGCTCAGG CTGAAGAAGA GAACAAGAAA GAAAAGCCGA GCTCCTGCAG GTATAGATTC 
CTTTGGAAAT TGCTGCTCGG GCTGCTGCTG ATCGCTCTGC TTTTTGGGAT TAAGATTCAT 
AGAGATAATG AGCTGGTGAG GCAGCAGGAG GCAGCACTGA GGACATTAGG GGCAGAGGGC 
CTCTTCCTTT TCTCCTCGCT GGACACAGAC AATGACATGC ACATCAGCCC TGAAGAGTTT 
AAGCCAATTT CGGAGAAGCT GACCGGGATT TCCACCACCT CCGACTACGA AGAGGAAGAG 
CTGCTAGATC CAAATGGAGA GACCTTGTCC GTGGCTTCAC GTTTCCAGCC TCTGCTCATG 
GAGACCATGA CAAAGAGCAA AGACGGGTTC TTGGGTATCA CTCACAGTGC TCTCTCTGGA 
CTTAGGAACT GGACTACACC GGTGGTGCCC AATAATGTGT TTTATGCCGG ACAGTTCAAG 
GCGTTCCTTC CACCCAAGAA CAAGTTAGAG GTGGGCAATC CTTGGTGGAT AATCCCTAGC 
GAGTTAAGCA TATTTACAGG GTACCTGCCT AATAACAGAA TTTATCCCCC GCCTCCCAAA 
GGGAAGGAGG TGATTATCCA TAAACTTTTG TCCATGTTTC ATCCGCGTCC TTTTATAAAA 
ACACGGTTTG CCCCTCAAGG CTCCGTAGCG TGCATCCGAG CCATCAGCGA TTTCTACTAC 
GACATCGTTT TCCGGATTCA CGCCGAGTTT CAGCTCAACG AACCTCCAAA TTTTCCTTTC 
TGGTTCTCCC CCGGTCAGTT CACCGGCAAT ATTGTCATCT CCAAAGACGC CGCTCACGTC 
CGGCACTTTA AGCTTTTCGT CCCCAATAAC CGCACCCTGA ACGTGGACAT GGAGTGGCTG 
TACGGCGCCA GCGAGAGCAG CAATATGGAG GTCGACATCG GTTACCTGCC GCAGATGGAA 
ATCGAATCTT TAGGACCGTC CATCCCGTCC ACGATCTACG ACGAGAACGG GAATATCATG 
GAAAGCCGGA ATGCAGAAGG AGAGGCTATA GAGTTTGTGT TTGAAGATAT AAACTGGCAG 
TCGGAGATGA CCTTTGAAGA AGCAGCCAGA AAACTCGAGG TCACCATGTA CCCATTTAAA 
AGGGTTTCTT ATTACCCTTT TCCAGAAGCT TTTGACCGTG CATTGGCAGA GAAGAAACTC 
GTGCATTCGG TTTTGCTCTG GGGGGCGCTG GACGACCAAT CTTGCTGAGG TTCGGGGCGA 
ACTCTCCGGG AGACCGTCCT AGAGAGTTTG CCCGTCCTTG CTTTGCTGAA CGAGAGCTTC 
ATTAGCACTT GGTCGTTAGT GAAGGAGCTC GAGGAGCTTC AGAGCAATAA AGACTCCTAC 
GCAACGTTTG CTTCACTCCA TTTGGAGAAG TACAACTTCC CGGTGGAGAT GATGATCTGC 
CTTCCCAACG GAACCGTGGT TCATCACATC AACGCAAATT ACTTCCTGGA CATCACCTCT 
CTGAAGCCGG ATGAAGTGGA GACCAACCTG TTTAGCTTCT CCGACGGCGT GGAGGATTTG 
TCCACCGTCA CTTACATCAA GTTCCTAAAG GAAGGGCTAG AGAAGGCCAA ACCATTCTTG 
CATTCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001070901.1
CDS	14..1702
Translation	MSADLRKRKKDTTADNDAPQEAQAEEENKKEKPSSCRYRFLWKLLLGLLLIALLFGIKIHRDNELVRQQEAALRTLGAEGLFLFSSLDTDNDMHISPEEFKPISEKLTGISTTSDYEEEELLDPNGETLSVASRFQPLLMETMTKSKDGFLGITHSALSGLRNWTTPVVPNNVFYAGQFKAFLPPKNKLEVGNPWWIIPSELSIFTGYLPNNRIYPPPPKGKEVIIHKLLSMFHPRPFIKTRFAPQGSVACIRAISDFYYDIVFRIHAEFQLNEPPNFPFWFSPGQFTGNIVISKDAAHVRHFKLFVPNNRTLNVDMEWLYGASESSNMEVDIGYLPQMEIESLGPSIPSTIYDENGNIMESRNAEGEAIEFVFEDINWQSEMTFEEAARKLEVTMYPFKRVSYYPFPEAFDRALAEKKLVHSVLLWGALDDQSC*GSGRTLRETVLESLPVLALLNESFISTWSLVKELEELQSNKDSYATFASLHLEKYNFPVEMMICLPNGTVVHHINANYFLDITSLKPDEVETNLFSFSDGVEDLSTVTYIKFLKEGLEKAKPFLHS

Target ORF information:

RefSeq Version	NM_001077433.2
Organism	Xenopus tropicalis(Tropical clawed frog)
Definition	Xenopus tropicalis selenoprotein N (selenon), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001077433.2

ORF Insert Sequence:

ATGTCAGCAG ATCTTCGAAA AAGAAAAAAA GACACCACTG CTGACAATGA TGCCCCACAG 
GAAGCTCAGG CTGAAGAAGA GAACAAGAAA GAAAAGCCGA GCTCCTGCAG GTATAGATTC 
CTTTGGAAAT TGCTGCTCGG GCTGCTGCTG ATCGCTCTGC TTTTTGGGAT TAAGATTCAT 
AGAGATAATG AGCTGGTGAG GCAGCAGGAG GCAGCACTGA GGACATTAGG GGCAGAGGGC 
CTCTTCCTTT TCTCCTCGCT GGACACAGAC AATGACATGC ACATCAGCCC TGAAGAGTTT 
AAGCCAATTT CGGAGAAGCT GACCGGGATT TCCACCACCT CCGACTACGA AGAGGAAGAG 
CTGCTAGATC CAAATGGAGA GACCTTGTCC GTGGCTTCAC GTTTCCAGCC TCTGCTCATG 
GAGACCATGA CAAAGAGCAA AGACGGGTTC TTGGGTATCA CTCACAGTGC TCTCTCTGGA 
CTTAGGAACT GGACTACACC GGTGGTGCCC AATAATGTGT TTTATGCCGG ACAGTTCAAG 
GCGTTCCTTC CACCCAAGAA CAAGTTAGAG GTGGGCAATC CTTGGTGGAT AATCCCTAGC 
GAGTTAAGCA TATTTACAGG GTACCTGCCT AATAACAGAA TTTATCCCCC GCCTCCCAAA 
GGGAAGGAGG TGATTATCCA TAAACTTTTG TCCATGTTTC ATCCGCGTCC TTTTATAAAA 
ACACGGTTTG CCCCTCAAGG CTCCGTAGCG TGCATCCGAG CCATCAGCGA TTTCTACTAC 
GACATCGTTT TCCGGATTCA CGCCGAGTTT CAGCTCAACG AACCTCCAAA TTTTCCTTTC 
TGGTTCTCCC CCGGTCAGTT CACCGGCAAT ATTGTCATCT CCAAAGACGC CGCTCACGTC 
CGGCACTTTA AGCTTTTCGT CCCCAATAAC CGCACCCTGA ACGTGGACAT GGAGTGGCTG 
TACGGCGCCA GCGAGAGCAG CAATATGGAG GTCGACATCG GTTACCTGCC GCAGATGGAA 
ATCGAATCTT TAGGACCGTC CATCCCGTCC ACGATCTACG ACGAGAACGG GAATATCATG 
GAAAGCCGGA ATGCAGAAGG AGAGGCTATA GAGTTTGTGT TTGAAGATAT AAACTGGCAG 
TCGGAGATGA CCTTTGAAGA AGCAGCCAGA AAACTCGAGG TCACCATGTA CCCATTTAAA 
AGGGTTTCTT ATTACCCTTT TCCAGAAGCT TTTGACCGTG CATTGGCAGA GAAGAAACTC 
GTGCATTCGG TTTTGCTCTG GGGGGCGCTG GACGACCAAT CTTGCTGAGG TTCGGGGCGA 
ACTCTCCGGG AGACCGTCCT AGAGAGTTTG CCCGTCCTTG CTTTGCTGAA CGAGAGCTTC 
ATTAGCACTT GGTCGTTAGT GAAGGAGCTC GAGGAGCTTC AGAGCAATAA AGACTCCTAC 
GCAACGTTTG CTTCACTCCA TTTGGAGAAG TACAACTTCC CGGTGGAGAT GATGATCTGC 
CTTCCCAACG GAACCGTGGT TCATCACATC AACGCAAATT ACTTCCTGGA CATCACCTCT 
CTGAAGCCGG ATGAAGTGGA GACCAACCTG TTTAGCTTCT CCGACGGCGT GGAGGATTTG 
TCCACCGTCA CTTACATCAA GTTCCTAAAG GAAGGGCTAG AGAAGGCCAA ACCATTCTTG 
CATTCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

selenon ( NM_001077433.3 ) cDNA ORF clone, Xenopus tropicalis(tropical clawed frog) -> NP_001070901.1 Xenopus tropicalis selenoprotein N (selenon), mRNA.

Price & Availability↑

CloneID	OXa00620
Clone ID Related Accession (Same CDS sequence)	NM_001077433.2 , NM_001077433.3
Accession Version	NM_001077433.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1689bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-17
Organism	Xenopus tropicalis(tropical clawed frog)
Product	selenoprotein N
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AAMC03038390.1. On Jul 22, 2017 this sequence version replaced NM_001077433.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: CR566474.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END##

ATGTCAGCAG ATCTTCGAAA AAGAAAAAAA GACACCACTG CTGACAATGA TGCCCCACAG 
GAAGCTCAGG CTGAAGAAGA GAACAAGAAA GAAAAGCCGA GCTCCTGCAG GTATAGATTC 
CTTTGGAAAT TGCTGCTCGG GCTGCTGCTG ATCGCTCTGC TTTTTGGGAT TAAGATTCAT 
AGAGATAATG AGCTGGTGAG GCAGCAGGAG GCAGCACTGA GGACATTAGG GGCAGAGGGC 
CTCTTCCTTT TCTCCTCGCT GGACACAGAC AATGACATGC ACATCAGCCC TGAAGAGTTT 
AAGCCAATTT CGGAGAAGCT GACCGGGATT TCCACCACCT CCGACTACGA AGAGGAAGAG 
CTGCTAGATC CAAATGGAGA GACCTTGTCC GTGGCTTCAC GTTTCCAGCC TCTGCTCATG 
GAGACCATGA CAAAGAGCAA AGACGGGTTC TTGGGTATCA CTCACAGTGC TCTCTCTGGA 
CTTAGGAACT GGACTACACC GGTGGTGCCC AATAATGTGT TTTATGCCGG ACAGTTCAAG 
GCGTTCCTTC CACCCAAGAA CAAGTTAGAG GTGGGCAATC CTTGGTGGAT AATCCCTAGC 
GAGTTAAGCA TATTTACAGG GTACCTGCCT AATAACAGAA TTTATCCCCC GCCTCCCAAA 
GGGAAGGAGG TGATTATCCA TAAACTTTTG TCCATGTTTC ATCCGCGTCC TTTTATAAAA 
ACACGGTTTG CCCCTCAAGG CTCCGTAGCG TGCATCCGAG CCATCAGCGA TTTCTACTAC 
GACATCGTTT TCCGGATTCA CGCCGAGTTT CAGCTCAACG AACCTCCAAA TTTTCCTTTC 
TGGTTCTCCC CCGGTCAGTT CACCGGCAAT ATTGTCATCT CCAAAGACGC CGCTCACGTC 
CGGCACTTTA AGCTTTTCGT CCCCAATAAC CGCACCCTGA ACGTGGACAT GGAGTGGCTG 
TACGGCGCCA GCGAGAGCAG CAATATGGAG GTCGACATCG GTTACCTGCC GCAGATGGAA 
ATCGAATCTT TAGGACCGTC CATCCCGTCC ACGATCTACG ACGAGAACGG GAATATCATG 
GAAAGCCGGA ATGCAGAAGG AGAGGCTATA GAGTTTGTGT TTGAAGATAT AAACTGGCAG 
TCGGAGATGA CCTTTGAAGA AGCAGCCAGA AAACTCGAGG TCACCATGTA CCCATTTAAA 
AGGGTTTCTT ATTACCCTTT TCCAGAAGCT TTTGACCGTG CATTGGCAGA GAAGAAACTC 
GTGCATTCGG TTTTGCTCTG GGGGGCGCTG GACGACCAAT CTTGCTGAGG TTCGGGGCGA 
ACTCTCCGGG AGACCGTCCT AGAGAGTTTG CCCGTCCTTG CTTTGCTGAA CGAGAGCTTC 
ATTAGCACTT GGTCGTTAGT GAAGGAGCTC GAGGAGCTTC AGAGCAATAA AGACTCCTAC 
GCAACGTTTG CTTCACTCCA TTTGGAGAAG TACAACTTCC CGGTGGAGAT GATGATCTGC 
CTTCCCAACG GAACCGTGGT TCATCACATC AACGCAAATT ACTTCCTGGA CATCACCTCT 
CTGAAGCCGG ATGAAGTGGA GACCAACCTG TTTAGCTTCT CCGACGGCGT GGAGGATTTG 
TCCACCGTCA CTTACATCAA GTTCCTAAAG GAAGGGCTAG AGAAGGCCAA ACCATTCTTG 
CATTCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001070901.1
CDS	14..1702
Translation	MSADLRKRKKDTTADNDAPQEAQAEEENKKEKPSSCRYRFLWKLLLGLLLIALLFGIKIHRDNELVRQQEAALRTLGAEGLFLFSSLDTDNDMHISPEEFKPISEKLTGISTTSDYEEEELLDPNGETLSVASRFQPLLMETMTKSKDGFLGITHSALSGLRNWTTPVVPNNVFYAGQFKAFLPPKNKLEVGNPWWIIPSELSIFTGYLPNNRIYPPPPKGKEVIIHKLLSMFHPRPFIKTRFAPQGSVACIRAISDFYYDIVFRIHAEFQLNEPPNFPFWFSPGQFTGNIVISKDAAHVRHFKLFVPNNRTLNVDMEWLYGASESSNMEVDIGYLPQMEIESLGPSIPSTIYDENGNIMESRNAEGEAIEFVFEDINWQSEMTFEEAARKLEVTMYPFKRVSYYPFPEAFDRALAEKKLVHSVLLWGALDDQSC*GSGRTLRETVLESLPVLALLNESFISTWSLVKELEELQSNKDSYATFASLHLEKYNFPVEMMICLPNGTVVHHINANYFLDITSLKPDEVETNLFSFSDGVEDLSTVTYIKFLKEGLEKAKPFLHS

Target ORF information:

RefSeq Version	NM_001077433.3
Organism	Xenopus tropicalis(tropical clawed frog)
Definition	Xenopus tropicalis selenoprotein N (selenon), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001077433.3

ORF Insert Sequence:

ATGTCAGCAG ATCTTCGAAA AAGAAAAAAA GACACCACTG CTGACAATGA TGCCCCACAG 
GAAGCTCAGG CTGAAGAAGA GAACAAGAAA GAAAAGCCGA GCTCCTGCAG GTATAGATTC 
CTTTGGAAAT TGCTGCTCGG GCTGCTGCTG ATCGCTCTGC TTTTTGGGAT TAAGATTCAT 
AGAGATAATG AGCTGGTGAG GCAGCAGGAG GCAGCACTGA GGACATTAGG GGCAGAGGGC 
CTCTTCCTTT TCTCCTCGCT GGACACAGAC AATGACATGC ACATCAGCCC TGAAGAGTTT 
AAGCCAATTT CGGAGAAGCT GACCGGGATT TCCACCACCT CCGACTACGA AGAGGAAGAG 
CTGCTAGATC CAAATGGAGA GACCTTGTCC GTGGCTTCAC GTTTCCAGCC TCTGCTCATG 
GAGACCATGA CAAAGAGCAA AGACGGGTTC TTGGGTATCA CTCACAGTGC TCTCTCTGGA 
CTTAGGAACT GGACTACACC GGTGGTGCCC AATAATGTGT TTTATGCCGG ACAGTTCAAG 
GCGTTCCTTC CACCCAAGAA CAAGTTAGAG GTGGGCAATC CTTGGTGGAT AATCCCTAGC 
GAGTTAAGCA TATTTACAGG GTACCTGCCT AATAACAGAA TTTATCCCCC GCCTCCCAAA 
GGGAAGGAGG TGATTATCCA TAAACTTTTG TCCATGTTTC ATCCGCGTCC TTTTATAAAA 
ACACGGTTTG CCCCTCAAGG CTCCGTAGCG TGCATCCGAG CCATCAGCGA TTTCTACTAC 
GACATCGTTT TCCGGATTCA CGCCGAGTTT CAGCTCAACG AACCTCCAAA TTTTCCTTTC 
TGGTTCTCCC CCGGTCAGTT CACCGGCAAT ATTGTCATCT CCAAAGACGC CGCTCACGTC 
CGGCACTTTA AGCTTTTCGT CCCCAATAAC CGCACCCTGA ACGTGGACAT GGAGTGGCTG 
TACGGCGCCA GCGAGAGCAG CAATATGGAG GTCGACATCG GTTACCTGCC GCAGATGGAA 
ATCGAATCTT TAGGACCGTC CATCCCGTCC ACGATCTACG ACGAGAACGG GAATATCATG 
GAAAGCCGGA ATGCAGAAGG AGAGGCTATA GAGTTTGTGT TTGAAGATAT AAACTGGCAG 
TCGGAGATGA CCTTTGAAGA AGCAGCCAGA AAACTCGAGG TCACCATGTA CCCATTTAAA 
AGGGTTTCTT ATTACCCTTT TCCAGAAGCT TTTGACCGTG CATTGGCAGA GAAGAAACTC 
GTGCATTCGG TTTTGCTCTG GGGGGCGCTG GACGACCAAT CTTGCTGAGG TTCGGGGCGA 
ACTCTCCGGG AGACCGTCCT AGAGAGTTTG CCCGTCCTTG CTTTGCTGAA CGAGAGCTTC 
ATTAGCACTT GGTCGTTAGT GAAGGAGCTC GAGGAGCTTC AGAGCAATAA AGACTCCTAC 
GCAACGTTTG CTTCACTCCA TTTGGAGAAG TACAACTTCC CGGTGGAGAT GATGATCTGC 
CTTCCCAACG GAACCGTGGT TCATCACATC AACGCAAATT ACTTCCTGGA CATCACCTCT 
CTGAAGCCGG ATGAAGTGGA GACCAACCTG TTTAGCTTCT CCGACGGCGT GGAGGATTTG 
TCCACCGTCA CTTACATCAA GTTCCTAAAG GAAGGGCTAG AGAAGGCCAA ACCATTCTTG 
CATTCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Selenoprotein Gene Nomenclature.
The Journal of biological chemistry291(46)24036-24040(2016 Nov)
Gladyshev VN,Arn?r ES,Berry MJ,Brigelius-Floh? R,Bruford EA,Burk RF,Carlson BA,Castellano S,Chavatte L,Conrad M,Copeland PR,Diamond AM,Driscoll DM,Ferreiro A,Floh? L,Green FR,Guig? R,Handy DE,Hatfield DL,Hesketh J,Hoffmann PR,Holmgren A,Hondal RJ,Howard MT,Huang K,Kim HY,Kim IY,K?hrle J,Krol A,Kryukov GV,Lee BJ,Lee BC,Lei XG,Liu Q,Lescure A,Lobanov AV,Loscalzo J,Maiorino M,Mariotti M,Sandeep Prabhu K,Rayman MP,Rozovsky S,Salinas G,Schmidt EE,Schomburg L,Schweizer U,Simonovi? M,Sunde RA,Tsuji PA,Tweedie S,Ursini F,Whanger PD,Zhang Y

Composition and evolution of the vertebrate and mammalian selenoproteomes.
PloS one7(3)e33066(2012)
Mariotti M,Ridge PG,Zhang Y,Lobanov AV,Pringle TH,Guigo R,Hatfield DL,Gladyshev VN

Recoding elements located adjacent to a subset of eukaryal selenocysteine-specifying UGA codons.
The EMBO journal24(8)1596-607(2005 Apr)
Howard MT,Aggarwal G,Anderson CB,Khatri S,Flanigan KM,Atkins JF

Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative.
Developmental dynamics : an official publication of the American Association of Anatomists225(4)384-91(2002 Dec)
Klein SL,Strausberg RL,Wagner L,Pontius J,Clifton SW,Richardson P

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selenon cDNA ORF clone, Xenopus tropicalis(tropical clawed frog)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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