Gene Symbol | selenot |
Entrez Gene ID | 394463 |
Full Name | selenoprotein T |
Synonyms | selt |
General protein information |
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Gene Type | protein-coding |
Organism | Xenopus tropicalis(tropical clawed frog) |
Summary | This gene encodes a selenoprotein, containing a selenocysteine (Sec) residue at the active site. Sec is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is localized in the endoplasmic reticulum. It belongs to the SelWTH family that possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. [provided by RefSeq, Jul 2017]. |