cyp19a1 cDNA ORF clone, Xenopus tropicalis(tropical clawed frog)

Gene
Clones
gRNAs

Summary

Gene Symbol	cyp19a1
Entrez Gene ID	100036594
Full Name	cytochrome P450 family 19 subfamily A member 1
Synonyms	aro,aromatase,cyp19
General protein information	Preferred Names cytochrome P450 family 19 subfamily A member 1 Names cytochrome P450 family 19 subfamily A member 1 P450 arom cytochrome P450 aromatase cytochrome P450, family 19, subfamily A, polypeptide 1
Gene Type	protein-coding
Organism	Xenopus tropicalis(tropical clawed frog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001097161.1	NP_001090630.1	cytochrome P450 family 19 subfamily A member 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CYP19A1	NP_112503.1
Canis lupus familiaris (dog)	CYP19A1	NP_001008715.1
Mus musculus (house mouse)	Cyp19a1	NP_031836.1
Rattus norvegicus (Norway rat)	Cyp19a1	NP_058781.2
Danio rerio (zebrafish)	cyp19a1b	NP_571717.1
Danio rerio (zebrafish)	cyp19a1a	NP_571229.2
Pan troglodytes (chimpanzee)	CYP19A1	XP_001169497.1
Gallus gallus (chicken)	CYP19A1	NP_001001761.1
	CYP19A1	XP_001082665.2
Bos taurus (cattle)	CYP19A1	NP_776730.1
Xenopus tropicalis (tropical clawed frog)	cyp19a1	NP_001090630.1

Gene Ontology
Bibliography

Related articles in PubMed

Early expression of aromatase and the membrane estrogen receptor GPER in neuromasts reveals a role for estrogens in the development of the frog lateral line system.
Hamilton CK, Navarro-Martin L, Neufeld M, Basak A, Trudeau VL
General and comparative endocrinology205242-50(2014 Sep)

Fadrozole and finasteride exposures modulate sex steroid- and thyroid hormone-related gene expression in Silurana (Xenopus) tropicalis early larval development.
Langlois VS, Duarte-Guterman P, Ing S, Pauli BD, Cooke GM, Trudeau VL
General and comparative endocrinology166(2)417-27(2010 Apr)

Xenopus W-linked DM-W induces Foxl2 and Cyp19 expression during ovary formation.
Okada E, Yoshimoto S, Ikeda N, Kanda H, Tamura K, Shiba T, Takamatsu N, Ito M
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation3(1)38-42(2009)

Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative.
Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW, Richardson P
Developmental dynamics : an official publication of the American Association of Anatomists225(4)384-91(2002 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The presence of estrogen-synthesizing enzyme aromatase and G protein-coupled estrogen receptor (GPER) proteins throughout early embryogenesis in the model organism, Silurana tropicalis, is demonstrated.
Title: Early expression of aromatase and the membrane estrogen receptor GPER in neuromasts reveals a role for estrogens in the development of the frog lateral line system.

Xenopus W-linked DM-W induces aromatase expression during ovary formation.
Title: Xenopus W-linked DM-W induces Foxl2 and Cyp19 expression during ovary formation.

The following cyp19a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the cyp19a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OXa02740	NM_001097161.1 Latest version!	Xenopus tropicalis cytochrome P450 family 19 subfamily A member 1 (cyp19a1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

cyp19a1 ( NM_001097161.1 ) cDNA ORF clone, Xenopus tropicalis(tropical clawed frog) -> NP_001090630.1 Xenopus tropicalis cytochrome P450 family 19 subfamily A member 1 (cyp19a1), mRNA.

Price & Availability↑

CloneID	OXa02740
Clone ID Related Accession (Same CDS sequence)	NM_001097161.1
Accession Version	NM_001097161.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1503bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-21
Organism	Xenopus tropicalis(tropical clawed frog)
Product	cytochrome P450 family 19 subfamily A member 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC118823.1. ##Evidence-Data-START## Transcript exon combination :: BC118823.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00028295, SAMD00028296 [ECO:0000350] ##Evidence-Data-END##

ATGGAAGCCT TGAATCCCGT GCAGTATAAC AGCACAGAGG CTGTTCCTAC TCTCGCACCT 
GCCACTACGG TTTCTCTCCT GCTCTTCATT TTTTTGCTTA TCATTCTATG GAATCAAGAG 
GAGACCTGTC TGATACCAGG CCCAGCCTAT TGCATGGGGC TTGGGCCCCT CATTTCTTAT 
GGCCGTTTTC TACTGACAGG AATTGGCAAA GCAGCAAATT ACTACAACAA CATGTACGGG 
GAATTTGTCA GAGTCTGGAT TAATGGCGAG GAAACACTGG TAATCAGCAA AGCTTCAGCA 
ACTTTTCACA TTATGAAGCA CAGCCATTAT ATCTCACGTT TTGGAAGCAA ACTGGGGCTG 
CAGTGTATTG GCATGAATGA AAACGGTATC ATATTTAATA GCAACCCATC TCTATGGAAG 
GTCATCCGAC CATTCTTCAT CAAAGCTTTG TCTGGTCCAG GACTTATGCA AACCACAGAA 
ATCTGTATAA GATCGACAAA ACGCTACCTG GATAACCTTG GCAATGTGAC AAATGAACTG 
GGAAATGTAG ATGTCCTTAA ACTAATGAGG CTTATTATGT TAGATACATC AAATAATCTC 
TTCTTAAGGA TACCTTTAGA TGAAAATGAA ATTGTTCTTA AAATCCAGAA ATACTTTGAC 
GCCTGGCAGG CTCTGCTTCT GAAACCAGAC ATCTTCTTTA AAATTTCCTG GCTGTACAAG 
AAATATGAAA AATCGGCAAA TGATCTGAAG GAGGCTATTG AAATTCTCAT TGAACAAAAA 
AGACAGAAAC TCTCAAGTTC TGAAAAGCTG GATGAAAATA TGGATTTTGC ATCAGAACTT 
ATTTTTGCCC AGAATCATGG AGATCTAACA GCTGAAAATG TCAATCAGTG TATTTTGGAA 
ATGCTGATAG CTGCTCCCGA TACCATGTCT GTATCTCTCT TCTTCATGTT GGTTCTGGTT 
GCTCAACACC CAAAGATAGA AGAAGGAATA ATGAATGAAA TTGATAATGT TATTGGTGAT 
CGGGATGTAG AGAGCAACGA CATTCCAAAT CTCAAAGTTC TGGAGAATTT TATTTATGAG 
AGCATGAGGT ACCAACCGGT TGTAGACCTG GTTATGCGCA AGGCCCTGGA GGACGATATG 
ATTGATGGTT ACTATGTGAA GAAAGGCACT AACATCATAT TAAACTTGGG GCGCATGCAC 
AGAATCGAAT ACTTTCCAAA GCCGAATGAG TTCACTTTGG AAAACTTTGA AAAGACGGTT 
CCATATCGTT ACTTTCAGCC CTTTGGCTCT GGCCCACGTG CTTGTGCGGG GAAGTACATA 
GCTATGGTTA TGATGAAAGT CATTCTGGTT ACTCTTTTCA AGAGGTACAA GGTGCAGACA 
CTGGGAGGAA GATGCTTGGA GAACATCCAA AACAACAATG ATTTGTCTAT GCACCCTGAT 
GAAAGCCAGC CATGCTTAGA GATGATTTTC ATTCCCAAGA ACACAGCAGA GCTCAAACAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001090630.1
CDS	268..1770
Translation	MEALNPVQYNSTEAVPTLAPATTVSLLLFIFLLIILWNQEETCLIPGPAYCMGLGPLISYGRFLLTGIGKAANYYNNMYGEFVRVWINGEETLVISKASATFHIMKHSHYISRFGSKLGLQCIGMNENGIIFNSNPSLWKVIRPFFIKALSGPGLMQTTEICIRSTKRYLDNLGNVTNELGNVDVLKLMRLIMLDTSNNLFLRIPLDENEIVLKIQKYFDAWQALLLKPDIFFKISWLYKKYEKSANDLKEAIEILIEQKRQKLSSSEKLDENMDFASELIFAQNHGDLTAENVNQCILEMLIAAPDTMSVSLFFMLVLVAQHPKIEEGIMNEIDNVIGDRDVESNDIPNLKVLENFIYESMRYQPVVDLVMRKALEDDMIDGYYVKKGTNIILNLGRMHRIEYFPKPNEFTLENFEKTVPYRYFQPFGSGPRACAGKYIAMVMMKVILVTLFKRYKVQTLGGRCLENIQNNNDLSMHPDESQPCLEMIFIPKNTAELKQ

Target ORF information:

RefSeq Version	NM_001097161.1
Organism	Xenopus tropicalis(tropical clawed frog)
Definition	Xenopus tropicalis cytochrome P450 family 19 subfamily A member 1 (cyp19a1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001097161.1

ORF Insert Sequence:

ATGGAAGCCT TGAATCCCGT GCAGTATAAC AGCACAGAGG CTGTTCCTAC TCTCGCACCT 
GCCACTACGG TTTCTCTCCT GCTCTTCATT TTTTTGCTTA TCATTCTATG GAATCAAGAG 
GAGACCTGTC TGATACCAGG CCCAGCCTAT TGCATGGGGC TTGGGCCCCT CATTTCTTAT 
GGCCGTTTTC TACTGACAGG AATTGGCAAA GCAGCAAATT ACTACAACAA CATGTACGGG 
GAATTTGTCA GAGTCTGGAT TAATGGCGAG GAAACACTGG TAATCAGCAA AGCTTCAGCA 
ACTTTTCACA TTATGAAGCA CAGCCATTAT ATCTCACGTT TTGGAAGCAA ACTGGGGCTG 
CAGTGTATTG GCATGAATGA AAACGGTATC ATATTTAATA GCAACCCATC TCTATGGAAG 
GTCATCCGAC CATTCTTCAT CAAAGCTTTG TCTGGTCCAG GACTTATGCA AACCACAGAA 
ATCTGTATAA GATCGACAAA ACGCTACCTG GATAACCTTG GCAATGTGAC AAATGAACTG 
GGAAATGTAG ATGTCCTTAA ACTAATGAGG CTTATTATGT TAGATACATC AAATAATCTC 
TTCTTAAGGA TACCTTTAGA TGAAAATGAA ATTGTTCTTA AAATCCAGAA ATACTTTGAC 
GCCTGGCAGG CTCTGCTTCT GAAACCAGAC ATCTTCTTTA AAATTTCCTG GCTGTACAAG 
AAATATGAAA AATCGGCAAA TGATCTGAAG GAGGCTATTG AAATTCTCAT TGAACAAAAA 
AGACAGAAAC TCTCAAGTTC TGAAAAGCTG GATGAAAATA TGGATTTTGC ATCAGAACTT 
ATTTTTGCCC AGAATCATGG AGATCTAACA GCTGAAAATG TCAATCAGTG TATTTTGGAA 
ATGCTGATAG CTGCTCCCGA TACCATGTCT GTATCTCTCT TCTTCATGTT GGTTCTGGTT 
GCTCAACACC CAAAGATAGA AGAAGGAATA ATGAATGAAA TTGATAATGT TATTGGTGAT 
CGGGATGTAG AGAGCAACGA CATTCCAAAT CTCAAAGTTC TGGAGAATTT TATTTATGAG 
AGCATGAGGT ACCAACCGGT TGTAGACCTG GTTATGCGCA AGGCCCTGGA GGACGATATG 
ATTGATGGTT ACTATGTGAA GAAAGGCACT AACATCATAT TAAACTTGGG GCGCATGCAC 
AGAATCGAAT ACTTTCCAAA GCCGAATGAG TTCACTTTGG AAAACTTTGA AAAGACGGTT 
CCATATCGTT ACTTTCAGCC CTTTGGCTCT GGCCCACGTG CTTGTGCGGG GAAGTACATA 
GCTATGGTTA TGATGAAAGT CATTCTGGTT ACTCTTTTCA AGAGGTACAA GGTGCAGACA 
CTGGGAGGAA GATGCTTGGA GAACATCCAA AACAACAATG ATTTGTCTAT GCACCCTGAT 
GAAAGCCAGC CATGCTTAGA GATGATTTTC ATTCCCAAGA ACACAGCAGA GCTCAAACAG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Early expression of aromatase and the membrane estrogen receptor GPER in neuromasts reveals a role for estrogens in the development of the frog lateral line system.
General and comparative endocrinology205242-50(2014 Sep)
Hamilton CK,Navarro-Martin L,Neufeld M,Basak A,Trudeau VL

Fadrozole and finasteride exposures modulate sex steroid- and thyroid hormone-related gene expression in Silurana (Xenopus) tropicalis early larval development.
General and comparative endocrinology166(2)417-27(2010 Apr)
Langlois VS,Duarte-Guterman P,Ing S,Pauli BD,Cooke GM,Trudeau VL

Xenopus W-linked DM-W induces Foxl2 and Cyp19 expression during ovary formation.
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation3(1)38-42(2009)
Okada E,Yoshimoto S,Ikeda N,Kanda H,Tamura K,Shiba T,Takamatsu N,Ito M

Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative.
Developmental dynamics : an official publication of the American Association of Anatomists225(4)384-91(2002 Dec)
Klein SL,Strausberg RL,Wagner L,Pontius J,Clifton SW,Richardson P

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cyp19a1 cDNA ORF clone, Xenopus tropicalis(tropical clawed frog)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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