Gene Symbol | OXCT1 |
Entrez Gene ID | 396978 |
Full Name | 3-oxoacid CoA-transferase 1 |
Synonyms | OXCT |
Gene Type | protein-coding |
Organism | Sus scrofa(pig) |
Genome |
ORF » Species Summary » Sus scrofa » OXCT1 cDNA ORF clone
Gene Symbol | OXCT1 |
Entrez Gene ID | 396978 |
Full Name | 3-oxoacid CoA-transferase 1 |
Synonyms | OXCT |
Gene Type | protein-coding |
Organism | Sus scrofa(pig) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_213938.1 | NP_999103.1 | succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial precursor |
Catalytic role of the conformational change in succinyl-CoA:3-oxoacid CoA transferase on binding CoA.
Fraser ME, Hayakawa K, Brown WD
Biochemistry49(48)10319-28(2010 Dec)
The high-resolution structure of pig heart succinyl-CoA:3-oxoacid coenzyme A transferase.
Coker SF, Lloyd AJ, Mitchell E, Lewis GR, Coker AR, Shoolingin-Jordan PM
Acta crystallographica. Section D, Biological crystallography66(Pt 7)797-805(2010 Jul)
Identification of the cysteine residue exposed by the conformational change in pig heart succinyl-CoA:3-ketoacid coenzyme A transferase on binding coenzyme A.
Tammam SD, Rochet JC, Fraser ME
Biochemistry46(38)10852-63(2007 Sep)
Structure of the CoA transferase from pig heart to 1.7 A resolution.
Coros AM, Swenson L, Wolodko WT, Fraser ME
Acta crystallographica. Section D, Biological crystallography60(Pt 10)1717-25(2004 Oct)
PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries.
Uenishi H, Eguchi T, Suzuki K, Sawazaki T, Toki D, Shinkai H, Okumura N, Hamasima N, Awata T
Nucleic acids research32(Database issue)D484-8(2004 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
mechanism of SCOT catalysis
Title: Catalytic role of the conformational change in succinyl-CoA:3-oxoacid CoA transferase on binding CoA.
On the basis of these results the conformational change in SCOT was deduced to be a domain rotation of 17 degrees coupled with movement of two loops: res. 321-329 that interact with succinate or acetoacetate and res. 374-386 that interact with CoA.
Title: Identification of the cysteine residue exposed by the conformational change in pig heart succinyl-CoA:3-ketoacid coenzyme A transferase on binding coenzyme A.
Structure of the CoA transferase from pig heart to 1.7 A resolution
Title: Structure of the CoA transferase from pig heart to 1.7 A resolution.
The following OXCT1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OXCT1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSe00552 | |
Clone ID Related Accession (Same CDS sequence) | NM_213938.1 | |
Accession Version | NM_213938.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1563bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-02 | |
Organism | Sus scrofa(pig) | |
Product | succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M80534.1. ##Evidence-Data-START## Transcript exon combination :: M80534.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1487420, SAMEA1876824 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## |
1 | ATGGCGGCTC TCACACTCCT CTCCTCCCGC CTGCGCCTCT GCGCCTCCGC CTACCGCTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_999103.1 |
CDS | 82..1644 |
Translation |
Target ORF information:
Target ORF information:
|
NM_213938.1 |
1 | ATGGCGGCTC TCACACTCCT CTCCTCCCGC CTGCGCCTCT GCGCCTCCGC CTACCGCTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Catalytic role of the conformational change in succinyl-CoA:3-oxoacid CoA transferase on binding CoA. |
The high-resolution structure of pig heart succinyl-CoA:3-oxoacid coenzyme A transferase. |
Identification of the cysteine residue exposed by the conformational change in pig heart succinyl-CoA:3-ketoacid coenzyme A transferase on binding coenzyme A. |
Structure of the CoA transferase from pig heart to 1.7 A resolution. |
PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. |