CXCR4 cDNA ORF clone, Sus scrofa(pig)

Gene
Clones
gRNAs

Summary

Gene Symbol	CXCR4
Entrez Gene ID	396659
Full Name	C-X-C motif chemokine receptor 4
Gene Type	protein-coding
Organism	Sus scrofa(pig)

mRNA and Protein(s)

mRNA	Protein	Name
NM_213773.1	NP_998938.1	C-X-C chemokine receptor type 4

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Initial assessment of the role of CXC chemokine receptor 4 after polytrauma.
Bach HH 4th, Saini V, Baker TA, Tripathi A, Gamelli RL, Majetschak M
Molecular medicine (Cambridge, Mass.)181056-66(2012 Sep)

Transmyocardial drilling revascularization combined with heparinized bFGF-incorporating stent activates resident cardiac stem cells via SDF-1/CXCR4 axis.
Zhang GW, Wen T, Gu TX, Li-Ling J, Wang C, Zhao Y, Liu J, Wang Y, Liu TJ, L? F
Experimental cell research318(4)391-9(2012 Feb)

Sequential patterns of chemokine- and chemokine receptor-synthesis following vessel wall injury in porcine coronary arteries.
Jabs A, Okamoto E, Vinten-Johansen J, Bauriedel G, Wilcox JN
Atherosclerosis192(1)75-84(2007 May)

PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries.
Uenishi H, Eguchi T, Suzuki K, Sawazaki T, Toki D, Shinkai H, Okumura N, Hamasima N, Awata T
Nucleic acids research32(Database issue)D484-8(2004 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CXCR4 controls leukocyte mobilization after trauma.
Title: Initial assessment of the role of CXC chemokine receptor 4 after polytrauma.

The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1/CXCR4 axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.
Title: Transmyocardial drilling revascularization combined with heparinized bFGF-incorporating stent activates resident cardiac stem cells via SDF-1/CXCR4 axis.

reports transmural and perivascular expression patterns of chemokines CCL2 and CXCL2 and of chemokine receptors CCR2, CCR5, and CXCR4 following coronary angioplasty
Title: Sequential patterns of chemokine- and chemokine receptor-synthesis following vessel wall injury in porcine coronary arteries.

The following CXCR4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CXCR4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSe30407	NM_213773.1 Latest version!	Sus scrofa C-X-C motif chemokine receptor 4 (CXCR4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CXCR4 ( NM_213773.1 ) cDNA ORF clone, Sus scrofa(pig) -> NP_998938.1 Sus scrofa C-X-C motif chemokine receptor 4 (CXCR4), mRNA.

Price & Availability↑

CloneID	OSe30407
Clone ID Related Accession (Same CDS sequence)	NM_213773.1
Accession Version	NM_213773.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Sus scrofa(pig)
Product	C-X-C chemokine receptor type 4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB116560.1. ##Evidence-Data-START## Transcript exon combination :: AB116560.1, DQ124104.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1487420, SAMEA1876824 [ECO:0000348] ##Evidence-Data-END##

ATGGACGGGT TCCGTATATT CACTTCAGAT AATTACACAG AGGATGACTT GGGCTCAGGT 
GACTATGACT CCATAAAGGA ACCCTGTTTC CGGGAGGAAA ATGCCCATTT CAACCGAATC 
TTTCTGCCCA CTGTCTACTC CATCATCTTC TTAACTGGCA TAGTGGGTAA TGGATTGGTC 
ATCCTGGTCA TGGGTTACCA GAAGAAACTG AGAAGCATGA CGGACAAGTA CAGACTGCAC 
CTGTCTGTGG CAGACCTTCT CTTTGTCCTC ACACTTCCCT TCTGGGCAGT TGATGCCGTG 
GCAAACTGGT ACTTTGGGAA GTTTCTGTGC AAGGCAGTCC ATGTCATCTA TACTGTCAAT 
CTCTACAGCA GTGTGCTCAT CCTGGCCTTC ATCAGTCTGG ACCGGTACCT GGCTATCGTC 
CATGCCACCA ACAGTCAGAG GCCAAGGAAG CTATTGGCTG AAAAAGTGGT CTATGTCGGC 
GTCTGGATAC CTGCCCTCCT GTTGACTATT CCTGATTTCA TCTTTGCGAA TGTCAGGGAG 
GGGGATGGGA GGTACATCTG TGACCGCTTC TACCCCAATG ACCTGTGGTT AGTGGTGTTC 
CAGTTTCAGC ACATCATGGT TGGCCTTATC CTGCCGGGTA TTGTCATCCT ATCTTGCTAT 
TGCATCATCA TCTCCAAGCT GTCCCACTCC AAGGGCTATC AGAAGCGCAA AGCTCTCAAA 
ACCACCGTTA TCCTCATCCT GGCTTTCTTC GCCTGCTGGC TGCCATACTA CATCGGGATC 
AGCATCGACT CCTTCATCCT CCTGGAAATC ATCCAGCAAG GGTGTGAGTT TGAGAGCACT 
GTGCACAAGT GGATTTCCAT CACTGAGGCC CTTGCCTTTT TCCACTGTTG CCTGAATCCT 
ATCCTCTACG CTTTCCTTGG AGCCAAATTT AAAACCTCTG CCCAGCACGC ACTCACCTCT 
GTGAGCAGAG GGTCCAGCCT AAAGATCCTC TCCAAGGGAA AGCGGGGTGG ACATTCTTCT 
GTTTCAACCG AGTCAGAGTC TTCGAGTTTT CACTCCAGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998938.1
CDS	1..1062
Translation	MDGFRIFTSDNYTEDDLGSGDYDSIKEPCFREENAHFNRIFLPTVYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVLTLPFWAVDAVANWYFGKFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVREGDGRYICDRFYPNDLWLVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGYQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIQQGCEFESTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS

Target ORF information:

RefSeq Version	NM_213773.1
Organism	Sus scrofa(pig)
Definition	Sus scrofa C-X-C motif chemokine receptor 4 (CXCR4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213773.1

ORF Insert Sequence:

ATGGACGGGT TCCGTATATT CACTTCAGAT AATTACACAG AGGATGACTT GGGCTCAGGT 
GACTATGACT CCATAAAGGA ACCCTGTTTC CGGGAGGAAA ATGCCCATTT CAACCGAATC 
TTTCTGCCCA CTGTCTACTC CATCATCTTC TTAACTGGCA TAGTGGGTAA TGGATTGGTC 
ATCCTGGTCA TGGGTTACCA GAAGAAACTG AGAAGCATGA CGGACAAGTA CAGACTGCAC 
CTGTCTGTGG CAGACCTTCT CTTTGTCCTC ACACTTCCCT TCTGGGCAGT TGATGCCGTG 
GCAAACTGGT ACTTTGGGAA GTTTCTGTGC AAGGCAGTCC ATGTCATCTA TACTGTCAAT 
CTCTACAGCA GTGTGCTCAT CCTGGCCTTC ATCAGTCTGG ACCGGTACCT GGCTATCGTC 
CATGCCACCA ACAGTCAGAG GCCAAGGAAG CTATTGGCTG AAAAAGTGGT CTATGTCGGC 
GTCTGGATAC CTGCCCTCCT GTTGACTATT CCTGATTTCA TCTTTGCGAA TGTCAGGGAG 
GGGGATGGGA GGTACATCTG TGACCGCTTC TACCCCAATG ACCTGTGGTT AGTGGTGTTC 
CAGTTTCAGC ACATCATGGT TGGCCTTATC CTGCCGGGTA TTGTCATCCT ATCTTGCTAT 
TGCATCATCA TCTCCAAGCT GTCCCACTCC AAGGGCTATC AGAAGCGCAA AGCTCTCAAA 
ACCACCGTTA TCCTCATCCT GGCTTTCTTC GCCTGCTGGC TGCCATACTA CATCGGGATC 
AGCATCGACT CCTTCATCCT CCTGGAAATC ATCCAGCAAG GGTGTGAGTT TGAGAGCACT 
GTGCACAAGT GGATTTCCAT CACTGAGGCC CTTGCCTTTT TCCACTGTTG CCTGAATCCT 
ATCCTCTACG CTTTCCTTGG AGCCAAATTT AAAACCTCTG CCCAGCACGC ACTCACCTCT 
GTGAGCAGAG GGTCCAGCCT AAAGATCCTC TCCAAGGGAA AGCGGGGTGG ACATTCTTCT 
GTTTCAACCG AGTCAGAGTC TTCGAGTTTT CACTCCAGCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Initial assessment of the role of CXC chemokine receptor 4 after polytrauma.
Molecular medicine (Cambridge, Mass.)181056-66(2012 Sep)
Bach HH 4th,Saini V,Baker TA,Tripathi A,Gamelli RL,Majetschak M

Transmyocardial drilling revascularization combined with heparinized bFGF-incorporating stent activates resident cardiac stem cells via SDF-1/CXCR4 axis.
Experimental cell research318(4)391-9(2012 Feb)
Zhang GW,Wen T,Gu TX,Li-Ling J,Wang C,Zhao Y,Liu J,Wang Y,Liu TJ,L? F

Sequential patterns of chemokine- and chemokine receptor-synthesis following vessel wall injury in porcine coronary arteries.
Atherosclerosis192(1)75-84(2007 May)
Jabs A,Okamoto E,Vinten-Johansen J,Bauriedel G,Wilcox JN

PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries.
Nucleic acids research32(Database issue)D484-8(2004 Jan)
Uenishi H,Eguchi T,Suzuki K,Sawazaki T,Toki D,Shinkai H,Okumura N,Hamasima N,Awata T