rrp6 cDNA ORF clone, Schizosaccharomyces pombe(fission yeast)

Gene
Clones
gRNAs

Summary

Gene Symbol	rrp6
Entrez Gene ID	2543630
Full Name	exosome 3'-5' exoribonuclease subunit Rrp6 (predicted)
Gene Type	protein-coding
Organism	Schizosaccharomyces pombe(fission yeast)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001018403.2	NP_593004.2	putative exosome 3'-5' exoribonuclease subunit Rrp6

Pathways from BioSystems

Homologies

Saccharomyces cerevisiae (baker's yeast)	RRP6	NP_014643.1
Neurospora crassa	NCU02256	XP_959900.1
Magnaporthe oryzae (rice blast fungus)	MGG_00896	XP_003718068.1
Eremothecium gossypii	AGOS_ACL001C	NP_983403.2
Kluyveromyces lactis	KLLA0D01309g	XP_453127.1
Schizosaccharomyces pombe (fission yeast)	rrp6	NP_593004.2

Gene Ontology
Bibliography

Related articles in PubMed

The genome sequence of Schizosaccharomyces pombe.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, D?sterh?ft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dr?ano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, S?nchez M, del Rey F, Benito J, Dom?nguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, Cerrutti L
Nature415(6874)871-80(2002 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Rrp6 may act as a structural adapter to target specific RNAs to the exosome by interacting with sequence-specific RNA-binding proteins.
Title: Relative contributions of the structural and catalytic roles of Rrp6 in exosomal degradation of individual mRNAs.

Pab2 and the nuclear exosome subunit, Rrp6 are the main factors involved in this polyadenylation-dependent pre-mRNA degradation pathway
Title: A Pre-mRNA degradation pathway that selectively targets intron-containing genes requires the nuclear poly(A)-binding protein.

The following rrp6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the rrp6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSc101756	NM_001018403.2 Latest version!	Schizosaccharomyces pombe putative exosome 3'-5' exoribonuclease subunit Rrp6 (rrp6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$426.30 $609.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

rrp6 ( NM_001018403.2 ) cDNA ORF clone, Schizosaccharomyces pombe(fission yeast) -> NP_593004.2 Schizosaccharomyces pombe putative exosome 3'-5' exoribonuclease subunit Rrp6 (rrp6), mRNA.

Price & Availability↑

CloneID	OSc101756
Clone ID Related Accession (Same CDS sequence)	NM_001018403.2
Accession Version	NM_001018403.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2334bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-04-02
Organism	Schizosaccharomyces pombe(fission yeast)
Product	putative exosome 3'-5' exoribonuclease subunit Rrp6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003424). On Dec 10, 2012 this sequence version replaced NM_001018403.1.

ATGGATGAGT CAGAATTGTT TAAGGGTTTA ATGAATAGTA CAGCCTATTG CTCTGAATTG 
GCAAAGGTTG ATATACCGTT TTATAAATCA ATTGATACCG AATTCAATGA AAACATAAAA 
AGTGTTTCTT CTCGTTTTAT GAGATTAATT GAATTGCTTC TTTCTAAAGT AGACAGAAGT 
CGGGCGGAGG ATATTGTGGA CGTTGAAGAT ATAGATAATA GATGGGCAGA AGTATCGGAC 
ACATTAGACA TACTCTTTGA AAAAGCTGAC TATTCTATCG ATAAAGCTCA AGGACTTTTA 
AAAAAGCCAG CGATCGAAAC CCATGCGTCG ACAAGCGATG TTGCCAATAA AAAACCAAAG 
AAAGAAAAGT TGCCCTACAA GGTTATTCAC GCAGCTCATC TTACTAAGCC TCAATTAAGG 
TTTCGAGTAC AGCCTAATAA TTCCAGGGAG TTTGTGTGGT CTTGGAAGTT AACTGAAAAA 
CCACATTCGT TAGTACCGCT CGAAAAGATT ATCGCTCAAG TCAAATTGGA CCCTAGTCTC 
AAAAACTCGT TACCACATCC ATATGAACCA GAAATACAAA ATAGCGTATA TCCTCCATGG 
GTTTCAGAAA TGTCTAATCC CATCGATACT GGCTCTGTCG ACGAAACAGA ACCTATCTGG 
GTTAGTACTG AAAGTCAGTT ATCGGATATG CTAAAAGAAT TACAAAACAG CAAAGAAATA 
GCCGTTGATC TTGAACACCA TGATTACAGA TCATTTAGAG GGTTCGTCTG TCTAATGCAA 
ATTAGTAATA GAGAAAAAGA TTGGATTGTT GACACCTTGG AACTCCGCGA AGAGCTTGAA 
GCTTTGAATG TTGTTTTTAC TAATCCAAAT ATCATTAAAG TTTTTCATGG TGCAACTATG 
GATATCATTT GGCTGCAAAG AGATTTCGGG CTTTACGTTG TAAACTTATT TGATACATAC 
TATGCTACTA AAGTTTTAGG ATTTGAGGGT CATGGTCTGG CTTTTCTGTT ACAAAAGTAT 
TGTGATTATG ATGCAGATAA AAGATACCAA ATGGCTGATT GGAGAATCCG TCCTTTGCCT 
CGGGAAATGT TAAAATATGC TCAATCTGAT ACGCATTATT TGTTATATAT TTGGGATCAT 
TTACGAAATG AACTCATATC AAAATCAGCT GAAAGAAAAG AAAATCTTAT GCAATCAGTG 
TTCAATTCCA GTAAACAAAT ATCTCTTAGA AAGTATGAAC TTGAGCCTTA TGATCCTATT 
TATGGACTTG GTACTGATGG CTGGAGAAAT GTACTTACTA AGTTTGGCTC TTCTAAAATA 
ATTGGACGGG AAGCTTTGAT GATTTATCGA GCACTGCACG ATTGGAGAGA TTCCGTAGCC 
CGAAAAGAAG ATGAAAGTGT TCGCTATGTG TTGCCAAATC GTTTACTTAT TGCGATTGCC 
GCCAGTAAAC CGGTTGAAGC GGCTGATGTG TTTTCAATTT CTAAGCAATT GACACCAATT 
GCTCGCATGT ATGTTGAAGA TATCGTTAAA GTCGTTCAAG AAGCCGAAAA GTTGTATAAT 
GAGCAAGTAG ATCGTGAGAA ATCCCAATTT AAAGAAGTTG AGAAGCAAAA TCAACCGCTA 
GCAGTTTTTT CCGAATCGAA TACTTTGGGT GATTACAAAG TTGACTCCAG TGTTTTCGAG 
ATTTCTAAAC AAAATAGAAG TAAACTAAAG ACTTTGCTGG CAAATGGATC TGCGTTTTGG 
ATTGAGGGAC AGTCGCAAGA TGATTTACGG AAAGCTCGTA AAGAGAGACT CTTTATAGTG 
AACCAGAATA TTCCTTTTTC ATTAACTCTT CCTTGTACTC AAGGGCATGT TGAATCCGAA 
TTGAATGTAA AGCAGTCCAC TGTAACTGAA GCTGCAAACC CGAGTCTGAA TGGAGAGAAG 
AAACAAGAGC CTATAGTCAT TAGGGATTTA GGGCTGAACA AGCAAAAAAG GGATTCTTCT 
AAGCTTAATC ATAAAGAACC CTCAAACCCC ATAGAGGAGC GAAATGAAGA TATTGAACCT 
TCGGAAGCTT CAACTTCAGT GTCAAAAAAA CGGAAGCAAA AGAAGAAAAA GAAGAACAGC 
GGAAAACTTA CTATTGAAGC CGAACATGTT TCTAATGACA GTCCAATTAT CAATGAAGCA 
CCTTTTGATT ATAAAAATCA AAAGAATTTT ATTGCTGACT TAGACTCTGA TGTAGGAAAA 
AATAAATTTG GGAAACGGGG TTTTAATCCT CTTAACAAGG TAAGTTTACC AAAGCGAAAT 
ACTAGGGAAC TCAAAAAAAG GAAGGTTTCA GACGGGAAGA GTACATCTTA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_593004.2
CDS	45..2378
Translation	MDESELFKGLMNSTAYCSELAKVDIPFYKSIDTEFNENIKSVSSRFMRLIELLLSKVDRSRAEDIVDVEDIDNRWAEVSDTLDILFEKADYSIDKAQGLLKKPAIETHASTSDVANKKPKKEKLPYKVIHAAHLTKPQLRFRVQPNNSREFVWSWKLTEKPHSLVPLEKIIAQVKLDPSLKNSLPHPYEPEIQNSVYPPWVSEMSNPIDTGSVDETEPIWVSTESQLSDMLKELQNSKEIAVDLEHHDYRSFRGFVCLMQISNREKDWIVDTLELREELEALNVVFTNPNIIKVFHGATMDIIWLQRDFGLYVVNLFDTYYATKVLGFEGHGLAFLLQKYCDYDADKRYQMADWRIRPLPREMLKYAQSDTHYLLYIWDHLRNELISKSAERKENLMQSVFNSSKQISLRKYELEPYDPIYGLGTDGWRNVLTKFGSSKIIGREALMIYRALHDWRDSVARKEDESVRYVLPNRLLIAIAASKPVEAADVFSISKQLTPIARMYVEDIVKVVQEAEKLYNEQVDREKSQFKEVEKQNQPLAVFSESNTLGDYKVDSSVFEISKQNRSKLKTLLANGSAFWIEGQSQDDLRKARKERLFIVNQNIPFSLTLPCTQGHVESELNVKQSTVTEAANPSLNGEKKQEPIVIRDLGLNKQKRDSSKLNHKEPSNPIEERNEDIEPSEASTSVSKKRKQKKKKKNSGKLTIEAEHVSNDSPIINEAPFDYKNQKNFIADLDSDVGKNKFGKRGFNPLNKVSLPKRNTRELKKRKVSDGKSTSY

Target ORF information:

RefSeq Version	NM_001018403.2
Organism	Schizosaccharomyces pombe(fission yeast)
Definition	Schizosaccharomyces pombe putative exosome 3'-5' exoribonuclease subunit Rrp6 (rrp6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001018403.2

ORF Insert Sequence:

ATGGATGAGT CAGAATTGTT TAAGGGTTTA ATGAATAGTA CAGCCTATTG CTCTGAATTG 
GCAAAGGTTG ATATACCGTT TTATAAATCA ATTGATACCG AATTCAATGA AAACATAAAA 
AGTGTTTCTT CTCGTTTTAT GAGATTAATT GAATTGCTTC TTTCTAAAGT AGACAGAAGT 
CGGGCGGAGG ATATTGTGGA CGTTGAAGAT ATAGATAATA GATGGGCAGA AGTATCGGAC 
ACATTAGACA TACTCTTTGA AAAAGCTGAC TATTCTATCG ATAAAGCTCA AGGACTTTTA 
AAAAAGCCAG CGATCGAAAC CCATGCGTCG ACAAGCGATG TTGCCAATAA AAAACCAAAG 
AAAGAAAAGT TGCCCTACAA GGTTATTCAC GCAGCTCATC TTACTAAGCC TCAATTAAGG 
TTTCGAGTAC AGCCTAATAA TTCCAGGGAG TTTGTGTGGT CTTGGAAGTT AACTGAAAAA 
CCACATTCGT TAGTACCGCT CGAAAAGATT ATCGCTCAAG TCAAATTGGA CCCTAGTCTC 
AAAAACTCGT TACCACATCC ATATGAACCA GAAATACAAA ATAGCGTATA TCCTCCATGG 
GTTTCAGAAA TGTCTAATCC CATCGATACT GGCTCTGTCG ACGAAACAGA ACCTATCTGG 
GTTAGTACTG AAAGTCAGTT ATCGGATATG CTAAAAGAAT TACAAAACAG CAAAGAAATA 
GCCGTTGATC TTGAACACCA TGATTACAGA TCATTTAGAG GGTTCGTCTG TCTAATGCAA 
ATTAGTAATA GAGAAAAAGA TTGGATTGTT GACACCTTGG AACTCCGCGA AGAGCTTGAA 
GCTTTGAATG TTGTTTTTAC TAATCCAAAT ATCATTAAAG TTTTTCATGG TGCAACTATG 
GATATCATTT GGCTGCAAAG AGATTTCGGG CTTTACGTTG TAAACTTATT TGATACATAC 
TATGCTACTA AAGTTTTAGG ATTTGAGGGT CATGGTCTGG CTTTTCTGTT ACAAAAGTAT 
TGTGATTATG ATGCAGATAA AAGATACCAA ATGGCTGATT GGAGAATCCG TCCTTTGCCT 
CGGGAAATGT TAAAATATGC TCAATCTGAT ACGCATTATT TGTTATATAT TTGGGATCAT 
TTACGAAATG AACTCATATC AAAATCAGCT GAAAGAAAAG AAAATCTTAT GCAATCAGTG 
TTCAATTCCA GTAAACAAAT ATCTCTTAGA AAGTATGAAC TTGAGCCTTA TGATCCTATT 
TATGGACTTG GTACTGATGG CTGGAGAAAT GTACTTACTA AGTTTGGCTC TTCTAAAATA 
ATTGGACGGG AAGCTTTGAT GATTTATCGA GCACTGCACG ATTGGAGAGA TTCCGTAGCC 
CGAAAAGAAG ATGAAAGTGT TCGCTATGTG TTGCCAAATC GTTTACTTAT TGCGATTGCC 
GCCAGTAAAC CGGTTGAAGC GGCTGATGTG TTTTCAATTT CTAAGCAATT GACACCAATT 
GCTCGCATGT ATGTTGAAGA TATCGTTAAA GTCGTTCAAG AAGCCGAAAA GTTGTATAAT 
GAGCAAGTAG ATCGTGAGAA ATCCCAATTT AAAGAAGTTG AGAAGCAAAA TCAACCGCTA 
GCAGTTTTTT CCGAATCGAA TACTTTGGGT GATTACAAAG TTGACTCCAG TGTTTTCGAG 
ATTTCTAAAC AAAATAGAAG TAAACTAAAG ACTTTGCTGG CAAATGGATC TGCGTTTTGG 
ATTGAGGGAC AGTCGCAAGA TGATTTACGG AAAGCTCGTA AAGAGAGACT CTTTATAGTG 
AACCAGAATA TTCCTTTTTC ATTAACTCTT CCTTGTACTC AAGGGCATGT TGAATCCGAA 
TTGAATGTAA AGCAGTCCAC TGTAACTGAA GCTGCAAACC CGAGTCTGAA TGGAGAGAAG 
AAACAAGAGC CTATAGTCAT TAGGGATTTA GGGCTGAACA AGCAAAAAAG GGATTCTTCT 
AAGCTTAATC ATAAAGAACC CTCAAACCCC ATAGAGGAGC GAAATGAAGA TATTGAACCT 
TCGGAAGCTT CAACTTCAGT GTCAAAAAAA CGGAAGCAAA AGAAGAAAAA GAAGAACAGC 
GGAAAACTTA CTATTGAAGC CGAACATGTT TCTAATGACA GTCCAATTAT CAATGAAGCA 
CCTTTTGATT ATAAAAATCA AAAGAATTTT ATTGCTGACT TAGACTCTGA TGTAGGAAAA 
AATAAATTTG GGAAACGGGG TTTTAATCCT CTTAACAAGG TAAGTTTACC AAAGCGAAAT 
ACTAGGGAAC TCAAAAAAAG GAAGGTTTCA GACGGGAAGA GTACATCTTA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The genome sequence of Schizosaccharomyces pombe.
Nature415(6874)871-80(2002 Feb)
Wood V,Gwilliam R,Rajandream MA,Lyne M,Lyne R,Stewart A,Sgouros J,Peat N,Hayles J,Baker S,Basham D,Bowman S,Brooks K,Brown D,Brown S,Chillingworth T,Churcher C,Collins M,Connor R,Cronin A,Davis P,Feltwell T,Fraser A,Gentles S,Goble A,Hamlin N,Harris D,Hidalgo J,Hodgson G,Holroyd S,Hornsby T,Howarth S,Huckle EJ,Hunt S,Jagels K,James K,Jones L,Jones M,Leather S,McDonald S,McLean J,Mooney P,Moule S,Mungall K,Murphy L,Niblett D,Odell C,Oliver K,O'Neil S,Pearson D,Quail MA,Rabbinowitsch E,Rutherford K,Rutter S,Saunders D,Seeger K,Sharp S,Skelton J,Simmonds M,Squares R,Squares S,Stevens K,Taylor K,Taylor RG,Tivey A,Walsh S,Warren T,Whitehead S,Woodward J,Volckaert G,Aert R,Robben J,Grymonprez B,Weltjens I,Vanstreels E,Rieger M,Sch?fer M,M?ller-Auer S,Gabel C,Fuchs M,D?sterh?ft A,Fritzc C,Holzer E,Moestl D,Hilbert H,Borzym K,Langer I,Beck A,Lehrach H,Reinhardt R,Pohl TM,Eger P,Zimmermann W,Wedler H,Wambutt R,Purnelle B,Goffeau A,Cadieu E,Dr?ano S,Gloux S,Lelaure V,Mottier S,Galibert F,Aves SJ,Xiang Z,Hunt C,Moore K,Hurst SM,Lucas M,Rochet M,Gaillardin C,Tallada VA,Garzon A,Thode G,Daga RR,Cruzado L,Jimenez J,S?nchez M,del Rey F,Benito J,Dom?nguez A,Revuelta JL,Moreno S,Armstrong J,Forsburg SL,Cerutti L,Lowe T,McCombie WR,Paulsen I,Potashkin J,Shpakovski GV,Ussery D,Barrell BG,Nurse P,Cerrutti L

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rrp6 cDNA ORF clone, Schizosaccharomyces pombe(fission yeast)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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