clr3 cDNA ORF clone, Schizosaccharomyces pombe(fission yeast)

Gene
Clones
gRNAs

Summary

Gene Symbol	clr3
Entrez Gene ID	2540821
Full Name	histone deacetylase (class II) Clr3
Gene Type	protein-coding
Organism	Schizosaccharomyces pombe(fission yeast)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001021011.2	NP_595104.1	class 2 histone deacetylase Clr3

Pathways from BioSystems

Homologies

Saccharomyces cerevisiae (baker's yeast)	HDA1	NP_014377.1
Schizosaccharomyces pombe (fission yeast)	clr3	NP_595104.1
Eremothecium gossypii	AGOS_ADL216C	NP_983880.2
Magnaporthe oryzae (rice blast fungus)	MGG_01076	XP_003717862.1
Kluyveromyces lactis	KLLA0E08383g	XP_454328.1
Neurospora crassa	NCU01525	XP_956974.2

Gene Ontology
Bibliography

Related articles in PubMed

The genome sequence of Schizosaccharomyces pombe.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, D?sterh?ft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dr?ano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, S?nchez M, del Rey F, Benito J, Dom?nguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, Cerrutti L
Nature415(6874)871-80(2002 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Heterochromatin assembly and transcriptome repression is mediated by Set1 in coordination with Clr3.
Title: Heterochromatin assembly and transcriptome repression by Set1 in coordination with a class II histone deacetylase.

Gcn5 is predominantly localized to coding regions of highly transcribed genes, where it collaborates antagonistically with the class-II histone deacetylase, Clr3, to modulate H3K14ac levels and transcriptional elongation.
Title: HAT-HDAC interplay modulates global histone H3K14 acetylation in gene-coding regions during stress.

The following clr3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the clr3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSc100189	NM_001021011.2 Latest version!	Schizosaccharomyces pombe class 2 histone deacetylase Clr3 (clr3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$426.30 $609.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

clr3 ( NM_001021011.2 ) cDNA ORF clone, Schizosaccharomyces pombe(fission yeast) -> NP_595104.1 Schizosaccharomyces pombe class 2 histone deacetylase Clr3 (clr3), mRNA.

Price & Availability↑

CloneID	OSc100189
Clone ID Related Accession (Same CDS sequence)	NM_001021011.2
Accession Version	NM_001021011.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2064bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-04-02
Organism	Schizosaccharomyces pombe(fission yeast)
Product	class 2 histone deacetylase Clr3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003423). On Dec 10, 2012 this sequence version replaced NM_001021011.1.

ATGCTGGCCT CTAATTCTGA TGGTGCATCT ACTTCTGTAA AACCATCCGA TGATGCTGTA 
AACACGGTAA CTCCATGGTC TATTCTTTTG ACAAACAATA AACCAATGTC TGGAAGTGAA 
AATACATTAA ATAACGAATC CCATGAAATG TCGCAAATCT TGAAAAAATC TGGATTATGC 
TATGATCCTC GAATGAGATT CCATGCCACT CTAAGTGAAG TGGATGACCA TCCTGAAGAT 
CCAAGACGCG TCCTTCGTGT TTTTGAAGCT ATAAAGAAGG CCGGTTATGT ATCTAATGTG 
CCGAGTCCGT CAGATGTATT TTTACGGATT CCGGCTAGAG AAGCTACTTT AGAAGAGTTA 
TTACAAGTTC ATTCACAGGA AATGTATGAT AGGGTTACTA ATACCGAAAA AATGTCTCAT 
GAGGATTTGG CCAATCTCGA AAAAATCAGT GATTCTCTAT ACTATAATAA CGAAAGTGCG 
TTTTGTGCTC GATTGGCTTG TGGTAGCGCA ATTGAAACAT GTACGGCTGT CGTAACTGGT 
CAAGTAAAAA ATGCCTTCGC AGTTGTTCGC CCTCCTGGCC ATCATGCAGA ACCCCATAAA 
CCTGGTGGCT TTTGTTTATT CAACAATGTT TCTGTAACCG CAAGGAGTAT GCTACAACGC 
TTTCCGGATA AAATAAAAAG AGTATTGATT GTCGACTGGG ATATACACCA TGGAAATGGT 
ACGCAAATGG CTTTTTATGA CGATCCAAAT GTTCTATACG TTTCTTTGCA TCGATATGAA 
AATGGTCGTT TCTATCCTGG CACCAATTAT GGGTGTGCAG AAAATTGTGG AGAGGGCCCG 
GGATTGGGTA GAACTGTAAA TATTCCTTGG AGTTGTGCTG GCATGGGAGA TGGTGATTAT 
ATATACGCTT TTCAGCGCGT CGTAATGCCT GTTGCTTATG AATTTGATCC AGATTTAGTT 
ATTGTAAGTT GCGGCTTTGA TGCTGCTGCA GGAGATCACA TTGGTCAATT CTTGTTAACT 
CCAGCTGCCT ATGCTCATAT GACACAAATG TTAATGGGAT TAGCAGATGG GAAAGTTTTT 
ATCTCCCTTG AGGGAGGTTA TAATTTGGAT TCTATAAGCA CATCAGCCTT AGCTGTAGCC 
CAAAGTTTGT TGGGAATTCC TCCTGGACGA TTGCATACAA CATATGCATG TCCACAGGCC 
GTTGCTACCA TCAACCATGT AACCAAAATA CAATCCCAAT ACTGGAGATG TATGAGGCCG 
AAACACTTCG ACGCAAATCC TAAGGATGCC CATGTAGATC GATTACATGA TGTTATTCGA 
ACTTATCAAG CTAAAAAACT TTTCGAAGAC TGGAAAATTA CCAATATGCC AATACTAAGG 
GATTCCGTTT CCAATGTATT CAACAATCAA GTACTGTGCT CTAGCAATTT CTTTCAAAAA 
GATAACCTTC TCGTTATTGT CCATGAATCT CCTAGAGTCC TGGGTAATGG AACTAGTGAA 
ACGAACGTTT TGAATTTAAA TGATTCGCTT TTAGTAGATC CCGTGAGCCT TTATGTTGAA 
TGGGCTATGC AACAGGACTG GGGGCTTATC GACATAAATA TACCTGAAGT GGTTACGGAC 
GGTGAAAATG CACCGGTTGA CATTCTTTCT GAAGTGAAAG AACTTTGTCT TTATGTATGG 
GATAATTATG TTGAGTTGTC GATTTCAAAA AATATTTTTT TCATCGGTGG AGGCAAAGCG 
GTACATGGAT TGGTTAATTT GGCATCTTCC AGGAATGTGT CAGACAGAGT TAAGTGTATG 
GTGAATTTCC TTGGCACTGA ACCTTTGGTG GGTCTTAAAA CGGCATCAGA GGAAGATCTT 
CCAACGTGGT ATTATCGTCA TTCACTCGTG TTTGTGAGTT CTAGTAATGA GTGCTGGAAA 
AAGGCAAAGC GTGCTAAAAG AAGATATGGA CGACTTATGC AAAGTGAACA TACTGAAACT 
TCGGACATGA TGGAGCAACA CTATCGAGCG GTTACTCAAT ACTTGCTGCA TTTGCTTCAA 
AAGGCCCGAC CAACTTCTCA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_595104.1
CDS	108..2171
Translation	MLASNSDGASTSVKPSDDAVNTVTPWSILLTNNKPMSGSENTLNNESHEMSQILKKSGLCYDPRMRFHATLSEVDDHPEDPRRVLRVFEAIKKAGYVSNVPSPSDVFLRIPAREATLEELLQVHSQEMYDRVTNTEKMSHEDLANLEKISDSLYYNNESAFCARLACGSAIETCTAVVTGQVKNAFAVVRPPGHHAEPHKPGGFCLFNNVSVTARSMLQRFPDKIKRVLIVDWDIHHGNGTQMAFYDDPNVLYVSLHRYENGRFYPGTNYGCAENCGEGPGLGRTVNIPWSCAGMGDGDYIYAFQRVVMPVAYEFDPDLVIVSCGFDAAAGDHIGQFLLTPAAYAHMTQMLMGLADGKVFISLEGGYNLDSISTSALAVAQSLLGIPPGRLHTTYACPQAVATINHVTKIQSQYWRCMRPKHFDANPKDAHVDRLHDVIRTYQAKKLFEDWKITNMPILRDSVSNVFNNQVLCSSNFFQKDNLLVIVHESPRVLGNGTSETNVLNLNDSLLVDPVSLYVEWAMQQDWGLIDINIPEVVTDGENAPVDILSEVKELCLYVWDNYVELSISKNIFFIGGGKAVHGLVNLASSRNVSDRVKCMVNFLGTEPLVGLKTASEEDLPTWYYRHSLVFVSSSNECWKKAKRAKRRYGRLMQSEHTETSDMMEQHYRAVTQYLLHLLQKARPTSQ

Target ORF information:

RefSeq Version	NM_001021011.2
Organism	Schizosaccharomyces pombe(fission yeast)
Definition	Schizosaccharomyces pombe class 2 histone deacetylase Clr3 (clr3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001021011.2

ORF Insert Sequence:

ATGCTGGCCT CTAATTCTGA TGGTGCATCT ACTTCTGTAA AACCATCCGA TGATGCTGTA 
AACACGGTAA CTCCATGGTC TATTCTTTTG ACAAACAATA AACCAATGTC TGGAAGTGAA 
AATACATTAA ATAACGAATC CCATGAAATG TCGCAAATCT TGAAAAAATC TGGATTATGC 
TATGATCCTC GAATGAGATT CCATGCCACT CTAAGTGAAG TGGATGACCA TCCTGAAGAT 
CCAAGACGCG TCCTTCGTGT TTTTGAAGCT ATAAAGAAGG CCGGTTATGT ATCTAATGTG 
CCGAGTCCGT CAGATGTATT TTTACGGATT CCGGCTAGAG AAGCTACTTT AGAAGAGTTA 
TTACAAGTTC ATTCACAGGA AATGTATGAT AGGGTTACTA ATACCGAAAA AATGTCTCAT 
GAGGATTTGG CCAATCTCGA AAAAATCAGT GATTCTCTAT ACTATAATAA CGAAAGTGCG 
TTTTGTGCTC GATTGGCTTG TGGTAGCGCA ATTGAAACAT GTACGGCTGT CGTAACTGGT 
CAAGTAAAAA ATGCCTTCGC AGTTGTTCGC CCTCCTGGCC ATCATGCAGA ACCCCATAAA 
CCTGGTGGCT TTTGTTTATT CAACAATGTT TCTGTAACCG CAAGGAGTAT GCTACAACGC 
TTTCCGGATA AAATAAAAAG AGTATTGATT GTCGACTGGG ATATACACCA TGGAAATGGT 
ACGCAAATGG CTTTTTATGA CGATCCAAAT GTTCTATACG TTTCTTTGCA TCGATATGAA 
AATGGTCGTT TCTATCCTGG CACCAATTAT GGGTGTGCAG AAAATTGTGG AGAGGGCCCG 
GGATTGGGTA GAACTGTAAA TATTCCTTGG AGTTGTGCTG GCATGGGAGA TGGTGATTAT 
ATATACGCTT TTCAGCGCGT CGTAATGCCT GTTGCTTATG AATTTGATCC AGATTTAGTT 
ATTGTAAGTT GCGGCTTTGA TGCTGCTGCA GGAGATCACA TTGGTCAATT CTTGTTAACT 
CCAGCTGCCT ATGCTCATAT GACACAAATG TTAATGGGAT TAGCAGATGG GAAAGTTTTT 
ATCTCCCTTG AGGGAGGTTA TAATTTGGAT TCTATAAGCA CATCAGCCTT AGCTGTAGCC 
CAAAGTTTGT TGGGAATTCC TCCTGGACGA TTGCATACAA CATATGCATG TCCACAGGCC 
GTTGCTACCA TCAACCATGT AACCAAAATA CAATCCCAAT ACTGGAGATG TATGAGGCCG 
AAACACTTCG ACGCAAATCC TAAGGATGCC CATGTAGATC GATTACATGA TGTTATTCGA 
ACTTATCAAG CTAAAAAACT TTTCGAAGAC TGGAAAATTA CCAATATGCC AATACTAAGG 
GATTCCGTTT CCAATGTATT CAACAATCAA GTACTGTGCT CTAGCAATTT CTTTCAAAAA 
GATAACCTTC TCGTTATTGT CCATGAATCT CCTAGAGTCC TGGGTAATGG AACTAGTGAA 
ACGAACGTTT TGAATTTAAA TGATTCGCTT TTAGTAGATC CCGTGAGCCT TTATGTTGAA 
TGGGCTATGC AACAGGACTG GGGGCTTATC GACATAAATA TACCTGAAGT GGTTACGGAC 
GGTGAAAATG CACCGGTTGA CATTCTTTCT GAAGTGAAAG AACTTTGTCT TTATGTATGG 
GATAATTATG TTGAGTTGTC GATTTCAAAA AATATTTTTT TCATCGGTGG AGGCAAAGCG 
GTACATGGAT TGGTTAATTT GGCATCTTCC AGGAATGTGT CAGACAGAGT TAAGTGTATG 
GTGAATTTCC TTGGCACTGA ACCTTTGGTG GGTCTTAAAA CGGCATCAGA GGAAGATCTT 
CCAACGTGGT ATTATCGTCA TTCACTCGTG TTTGTGAGTT CTAGTAATGA GTGCTGGAAA 
AAGGCAAAGC GTGCTAAAAG AAGATATGGA CGACTTATGC AAAGTGAACA TACTGAAACT 
TCGGACATGA TGGAGCAACA CTATCGAGCG GTTACTCAAT ACTTGCTGCA TTTGCTTCAA 
AAGGCCCGAC CAACTTCTCA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The genome sequence of Schizosaccharomyces pombe.
Nature415(6874)871-80(2002 Feb)
Wood V,Gwilliam R,Rajandream MA,Lyne M,Lyne R,Stewart A,Sgouros J,Peat N,Hayles J,Baker S,Basham D,Bowman S,Brooks K,Brown D,Brown S,Chillingworth T,Churcher C,Collins M,Connor R,Cronin A,Davis P,Feltwell T,Fraser A,Gentles S,Goble A,Hamlin N,Harris D,Hidalgo J,Hodgson G,Holroyd S,Hornsby T,Howarth S,Huckle EJ,Hunt S,Jagels K,James K,Jones L,Jones M,Leather S,McDonald S,McLean J,Mooney P,Moule S,Mungall K,Murphy L,Niblett D,Odell C,Oliver K,O'Neil S,Pearson D,Quail MA,Rabbinowitsch E,Rutherford K,Rutter S,Saunders D,Seeger K,Sharp S,Skelton J,Simmonds M,Squares R,Squares S,Stevens K,Taylor K,Taylor RG,Tivey A,Walsh S,Warren T,Whitehead S,Woodward J,Volckaert G,Aert R,Robben J,Grymonprez B,Weltjens I,Vanstreels E,Rieger M,Sch?fer M,M?ller-Auer S,Gabel C,Fuchs M,D?sterh?ft A,Fritzc C,Holzer E,Moestl D,Hilbert H,Borzym K,Langer I,Beck A,Lehrach H,Reinhardt R,Pohl TM,Eger P,Zimmermann W,Wedler H,Wambutt R,Purnelle B,Goffeau A,Cadieu E,Dr?ano S,Gloux S,Lelaure V,Mottier S,Galibert F,Aves SJ,Xiang Z,Hunt C,Moore K,Hurst SM,Lucas M,Rochet M,Gaillardin C,Tallada VA,Garzon A,Thode G,Daga RR,Cruzado L,Jimenez J,S?nchez M,del Rey F,Benito J,Dom?nguez A,Revuelta JL,Moreno S,Armstrong J,Forsburg SL,Cerutti L,Lowe T,McCombie WR,Paulsen I,Potashkin J,Shpakovski GV,Ussery D,Barrell BG,Nurse P,Cerrutti L

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clr3 cDNA ORF clone, Schizosaccharomyces pombe(fission yeast)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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