Gene Symbol | pku70 |
Entrez Gene ID | 2539090 |
Full Name | Ku domain protein Pku70 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
ORF » Species Summary » Schizosaccharomyces pombe » pku70 cDNA ORF clone
Gene Symbol | pku70 |
Entrez Gene ID | 2539090 |
Full Name | Ku domain protein Pku70 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
mRNA | Protein | Name |
---|---|---|
NM_001023436.2 | NP_588445.1 | Ku domain protein Pku70 |
NM_001355945.1 | NP_001342782.1 | Ku domain protein Pku70 |
XRCC6 | XP_001105684.1 | |
Gallus gallus (chicken) | XRCC6 | NP_990258.1 |
Danio rerio (zebrafish) | LOC100536337 | XP_003199637.1 |
Canis lupus familiaris (dog) | XRCC6 | XP_005625882.1 |
Mus musculus (house mouse) | Xrcc6 | NP_034377.2 |
Neurospora crassa | NCU08290 | XP_962503.2 |
Xenopus tropicalis (tropical clawed frog) | xrcc6 | NP_001005700.1 |
Danio rerio (zebrafish) | xrcc6 | NP_956198.1 |
Arabidopsis thaliana (thale cress) | KU70 | NP_564012.1 |
Bos taurus (cattle) | XRCC6 | NP_001179175.1 |
Rattus norvegicus (Norway rat) | Xrcc6 | NP_620780.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002690 | XP_312232.5 |
Kluyveromyces lactis | KLLA0C06226g | XP_452475.1 |
Schizosaccharomyces pombe (fission yeast) | pku70 | NP_588445.1 |
Oryza sativa (rice) | Os07g0184900 | NP_001059061.1 |
Homo sapiens (human) | XRCC6 | NP_001460.1 |
Pan troglodytes (chimpanzee) | XRCC6 | XP_521301.3 |
Drosophila melanogaster (fruit fly) | Irbp | NP_536773.1 |
Caenorhabditis elegans (roundworm) | cku-70 | NP_499438.2 |
Saccharomyces cerevisiae (baker's yeast) | YKU70 | NP_014011.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01512 | XP_003714485.1 |
The genome sequence of Schizosaccharomyces pombe.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, D?sterh?ft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dr?ano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, S?nchez M, del Rey F, Benito J, Dom?nguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, Cerrutti L
Nature415(6874)871-80(2002 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results suggest the possibility that Ku proteins (pku70, pku80)play an important role in genome integrity recovering replication stress.
Title: Fission yeast Ku protein is required for recovery from DNA replication stress.
potential relevance of Bin1-Ku interaction to cancer are discussed in light of these findings
Title: Bin1 interacts with and restrains the DNA end-binding protein complex Ku.
Pku70 inhibited microhomology-mediated end-joining and increased the minimal homology length required for efficient microhomology-mediated end-joining
Title: Microhomology-mediated end joining in fission yeast is repressed by pku70 and relies on genes involved in homologous recombination.
The following pku70 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the pku70 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSj00438 | |
Clone ID Related Accession (Same CDS sequence) | NM_001023436.2 | |
Accession Version | NM_001023436.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1824bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2013-04-30 | |
Organism | Schizosaccharomyces pombe 972h- | |
Product | Ku domain protein Pku70 | |
Comment | PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003421). On Dec 10, 2012 this sequence version replaced NM_001023436.1. Notes: S. pombe (fission yeast) sequence and annotation are available from: (URL, http://www.genedb.org/genedb/pombe/index.jsp) (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CDS are numbered using the following system eg SPAC5H10.01c. SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), .01 (first CDS), c (complementary strand). However, clones may have been reorientated since the original submission, therefore the complementary strand notation may be invalid for strand inference. |
1 | ATGGAAAACG ATGAACAAAT AGATGAGACA GAAAATTTTG CAATTGGAAA ATATGCCATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_588445.1 |
CDS | 282..2105 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001023436.2 |
1 | ATGGAAAACG ATGAACAAAT AGATGAGACA GAAAATTTTG CAATTGGAAA ATATGCCATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSc99563 | |
Clone ID Related Accession (Same CDS sequence) | NM_001355945.1 | |
Accession Version | NM_001355945.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1824bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-04-02 | |
Organism | Schizosaccharomyces pombe(fission yeast) | |
Product | Ku domain protein Pku70 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003421). |
1 | ATGGAAAACG ATGAACAAAT AGATGAGACA GAAAATTTTG CAATTGGAAA ATATGCCATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001342782.1 |
CDS | 233..2056 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001355945.1 |
1 | ATGGAAAACG ATGAACAAAT AGATGAGACA GAAAATTTTG CAATTGGAAA ATATGCCATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The genome sequence of Schizosaccharomyces pombe. |